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008			141015s2014 gw | s |||| 0|eng d
020			_a9783319080840
050		4	_aR857.N34 _bN35 2014 EB
082	0	4	_a615.19
245	0	0	_aNano-Oncologicals : _bNew Targeting and Delivery Approaches _cedited by Maria José Alonso, Marcos Garcia-Fuentes
264		1	_aCham, Switzerland _bSpringer _c2014
300			_a1 recurso en línea (XIV, 473 p.) _b58 ilustraciones, 51 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aAdvances in Delivery Science and Technology _x2192-6204
505	0		_a1 Passive vs active targeting: an update of the EPR role in drug delivery to tumors -- 2 The “EXâ€{u086E}d the “SOMAâ€{uA808}ow they communicate -- 3 Polymeric nano carriers for cancer therapy -- 4 Targeted Liposomes and Micelles as Carriers for Cancer Therapy -- 5 Photodynamic therapy for cancer: principles, clinical applications and nano technological approaches -- 6 Cancer Vaccines: fundamentals and strategies -- 7 Cancer immune modulation and immunosuppressive cells: current and future therapeutic approaches -- 8 Nanotechnology and cáncer immunomodulation -- 9 RNAi-based Nano-Oncologicals â€ĥlivery and Clinical Applications -- 10 Nano-Platforms for Tumor-Targeted Delivery of Nucleic Acid Therapies -- 11 Multifunctional Gold Nano carriers for Cancer Theranostics â€{u01B2}om bench to bedside and back again? -- 12 Micro bubbles as Theranostics Agents -- 13 Multimodal Nano-Systems for Cancer Diagnosis, Imaging and Therapy -- 14 Nano toxicology: Towards Safety-by-Design -- 15 Regulatory aspects of oncologicals: nano systems main challenges -- 16 BO-110, a dsRNA-based anticancer treatment.
520			_aThis authoritative volume focuses on emerging technologies in cancer nanomedicine, characterized by their multi-functionality and potential to address simultaneously diverse issues of clinical relevance in the treatment of cancer. The book consists of sixteen chapters divided into six sections: 1) Biological Barriers in Cancer; 2) Tumor Targeting; 3) Targeting the Immune System; 4) Gene Therapy; 5) Nanotheranostics; and 6) Translational Aspects of Nano-Oncologicals. The volume starts with an introduction describing the biological barriers associated with cancer therapy and highlighting ways to overcome such barriers through the use of nanotechnology. This is followed by an analysis of the two major targeting strategies currently under investigation in cancer therapy: namely, the targeting of cancer cells and the targeting of the immune system. In the first case, the book presents liposomal and polymer-based therapies, including photodynamic approaches. In the second case, it analyzes in detail the possibility of either improving the efficiency of the immune system toward preventing cancer progression (cancer immunomodulation) or generating responses against specific cancer antigens (cancer vaccines). Beyond these targeting options, Nano-Oncologicals: New Targeting and Delivery Approaches presents the most recent technological advances in the area of nucleic acid-based therapies, along with those in the area of theranostics, where the design of multifunctional nanocarriers becomes vital. Following the study of the most promising nanotechnologies around the development of nano-oncologicals, the book ends with an overview of regulatory and toxicological issues, which are critical in their translational pathway, and the presentation of a nucleic acid-based therapy case-study. This book is an important resource for scientists interested in the design and development of anticancer nanotechnologies and also to those aiming to push their technology through clinical development.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER
650		7	_aNanotecnología _0comprobar BNE20011268513 _2embne _9158453
700	1		_aAlonso, Maria José _eeditor literario _96744 _0comprobar BNE19900625193
700	1		_aGarcia-Fuentes, Marcos _eeditor literario _986849 _0Local
830		0	_aAdvances in Delivery Science and Technology _x2192-6204 _9133164
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-08084-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319080840
907			_a.b12843507 _b10-10-17 _c23-02-15
998			_am _a_alco _a_vill _b16-09-17 _cm _dz _ef _feng _ggw _h0
945			_aR857 .N34 N35 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11556419 _z06-04-17
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