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020 _a9781493918560
024 7 _a10.1007/978-1-4939-1856-0
_2doi
040 _dES-MaUEC
050 4 _aRB127
_b.F357 2014
100 1 _aFairbanks, Carolyn A.
_eeditor literario
_986832
_0Local
245 1 0 _aNeurobiological Studies of Addiction in Chronic Pain States
_cedited by Carolyn A. Fairbanks, Thomas J. Martin, Ph.D.
260 _aNew York
_bSpringer International Publishing
_c2014
300 _a1 recurso en línea (XII, 132 p.)
_b7 ilustraciones, 3 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aContemporary Clinical Neuroscience
_v17
505 0 _aOpioid and Non-Opioid Drug Responding Under States of Chronic Pain: A Timeline Spanning 1980 to Present Day -- Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction -- The Influence of Pain on Reward Processing: Current Literature and Prospects -- Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward -- Drug Addiction and Chronic Pain: A Review of Animal Models -- Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary -- Prenatal Exposure to Opioids -- Opioids in an Evidence-Based World.
520 _aUsing rodent models, the contributors explore the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction. Combining various pain models with opioid self-administration and central administration pharmacotherapies allows researchers to answer important questions about: 1. The efficacy of opioid treatment under conditions of chronic pain of different etiology. 2. Alterations in the efficacy of opioid treatment under conditions of long-term opioid pharmacotherapy. 3. The potential for conversion or escalation of extra-analgesic motivation for opioid use beyond that required for pain relief. 4. The possibility of addiction development in chronic pain sufferers. Merging the field of pain researchers with that of addiction research has presented some unique challenges and this volume seeks to provide some guidance for future study design in addition to a summary of current findings in the area.
650 7 _2embne
_9170361
_aDolor
_xTratamiento
700 1 _aMartin, Ph.D., Thomas J
_eeditor literario
_986833
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-1856-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12843404
_b10-10-17
_c23-02-15
942 _2lcc
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945 _aRB127 .F357 2014 EB
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