000 03701nam a22003855i 4500
999 _c77849
_d77849
_x1
001 77849
003 ES-MaUEC
005 20230207040247.0
007 cr nn 008mamaa
008 141111s2014 xxu| s |||| 0|eng d
020 _a9781493911677
024 7 _a10.1007/978-1-4939-1167-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP364.7
_bL478 2014
082 0 4 _a612.8
100 1 _aLester, Robin A. J.
_eeditor.
_0Local
_986808
245 1 0 _aNicotinic Receptors
_cedited by Robin A.J. Lester.
260 _aNew York, NY
_bSpringer New York
_bImprint: Humana Press
_c2014.
300 _a1 recurso en línea (XVII, 461 p.)
_b42 ilustraciones, 31 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aThe Receptors
_v26
505 0 _aOn the Discovery of the Nicotinic Acetylcholine Receptor Channel -- Molecular Structure and Gating -- Molecular Underpinnings of Neuronal Nicotinic Acetylcholine Receptor Expression -- Presynaptic Nicotinic Receptors: Subtypes and Function -- Functional Distribution and Regulation of Neuronal Nicotinic Acetylcholine Receptors in the Mammalian Brain -- Nicotinic Signaling in Development -- Presynaptic Nicotinic Acetylcholine Receptors & The Modulation Of Circuit Excitability -- Autonomic Nervous System Transmission -- Nicotinic Receptors in the Spinal Cord -- Slow Synaptic Transmission in the Central Nervous System -- The Effects of Nicotine on Learning and Memory -- Nicotinic Receptors as Targets for Novel Analgesics and Anti-Inflammatory Drugs -- Nicotinic Acetylcholine Receptors and the Roles of the Alpha7 Subunit -- Role of Central Serotonin Receptors in Nicotine Addiction -- Neuronal Nicotinic Acetylcholine Receptors in Reward and Addiction -- Genetic Contributions of the α5 Nicotinic Receptor Subunit to Smoking Behavior -- Smokingâ€{u296C}ated Genes and Functional Consequences -- Nicotinic Acetylcholine Receptors Along the Habenulo-Interpeduncular Pathway: Roles in Nicotine Withdrawal and Other Aversive Aspects -- Nicotinic Acetylcholine Receptors in Alzheimerâ€{u3821}nd Parkinsonâ€{u3804}isease -- Nicotinic Receptors and Mental Illness -- Current & Future Trends in Drug Discovery and Development Related to Nicotinic Receptors.
520 _aA comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets. It includes background information on all subtypes of nicotinic receptors, the most recent information on the distribution throughout the nervous system, and discussion of their implications in learning and memory, addiction, and neurological and psychiatric disease such as Alzheimer's and Parkinson's. Takes advantage of several recent developments in the fields of optogenetics, viral expression, and gene analysis to focus on current knowledge on the functional aspects of nicotinic receptors.
650 7 _9146728
_aNeuroquímica
_2embne
710 2 _aSpringerLink (Online service)
_0Local
_9106996
830 0 _aThe Receptors
_v26
_9133208
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-1167-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12843283
_b10-10-17
_c23-02-15
942 _2lcc
_cLE
945 _aQP364.7 L478 2014 EB
_g1
_ieBOOK
_j0
_lmae
_o-
_pEUR0.00
_q-
_r-
_sb
_t15
_u0
_v0
_w0
_x0
_y.i11556195
_z06-04-17
988 _aEBOOK, EBSPRINGER
998 _am
_a_alco
_a_vill
_b - -
_cm
_dz
_e-
_feng
_gxxu
_h0