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008			140428s2014 ne | s |||| 0|eng d
020			_a9789401787543
024	7		_a10.1007/978-94-017-8754-3 _2doi
040			_dES-MaUEC
050		4	_aQH588.S83 _bG736 2014
100	1		_aGrande, Enrique. _eeditor literario _929598 _0comprobar BNE19999412062
245	1	0	_aStem Cells in Cancer: Should We Believe or Not? _cedited by Enrique Grande, Luis Antón Aparicio
260			_aDordrecht, Netherlands _bSpringer International Publishing _c2014
300			_a1 recurso en línea (VIII, 299 p.) _b23 ilustraciones, 19 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aForeword -- The universal stem cell: does it exist? -- What is the meaning of Notch pathway and how we can selectively do the targeting -- Hedhehog as a new paradigm in cancer treatment Stem cells in cancer: should we believe or not? -- Wnt pathway at a glance: from the deep of the crypts to the current ways of targeting -- Cancer Stem Cells in Brest Cancer -- Â{u386E}ncer Stem Cells in Colon Cancer -- Cancer Stem Cells in Genitourinary Cancer -- Cancer Stem Cells in Pancreatic Cancer -- Cancer Stem Cells in Gastric Cancer -- Cancer Stem Cells in Melanoma -- Cancer Stem Cells in Brain Tumors -- Cancer Stem Cells in Sarcomas -- Cancer Stem Cells in Gynecologic Tumors.
520			_aThis volume explores the latest developments in a novel area of molecular biology and a hot topic in the field of oncology: cancer stem cells. These chapters from expert contributing authors present concepts such as the universal stem cell, new molecular pathways, new targeted agents, the different roles that cancer stem cells seem to have according to the organ they are placed in, and the future role that targeting cancer stem cells may have in the management of patients in the clinic. Â{u2820} Exploring the latest research including new data from randomized trials, this book examines important proposals over the origin of cancer stem cells such as the possibility that cancer stem cells may arise from mutated stem cells or a fully differentiated cell that may undergo several mutations that drive it back to a stem-like state. The authors consider the role that stem cells seem to have in the onset, development and resistance to classical antitumoral treatments of cancer and discuss possible potential future treatment modalities for the management of advanced cancer patients.The question, "Are stem cells involved in cancer?" may not have a simple answer, but ongoing investigations, in-depth consideration and a broad spectrum of information can be found in this book, allowing the reader to arrive at his or her own answer. This book will appeal to researchers in the field of oncology and cancer research and biomedical scientists with an interest in stem cells.
650		7	_2embne _aCélulas madre _9160528
700	1		_aAntón Aparicio, Luis _eeditor literario _0Local _986337
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-017-8754-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12825505 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQH588.S83 G736 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1155471x _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h0