000			04195nam a22003975i 4500
001			76887
003			ES-MaUEC
005			20230207040243.0
007			cr nn 008mamaa
008			131113s2014 ne | s |||| 0|eng d
020			_a9789400775695
024	7		_a10.1007/978-94-007-7569-5 _2doi
050		4	_aRC280.B6 _bV377 2014
100	1		_aVassiliou, Vassilios. _eeditor. _986264 _0Local
245	1	0	_aBone Metastases : _bA translational and Clinical Approach _cedited by Vassilios Vassiliou, Edward Chow, Dimitrios Kardamakis.
250			_a2nd ed. 2014.
260			_aDordrecht, Netherlands _bSpringer _c2014
300			_a1 recurso en línea (IX, 490 páginas) _b54 ilustraciones, 20 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aCancer Metastasis - Biology and Treatment _x1568-2102 _v21
505	0		_aPreface. I Fundamental Concepts -- Pathophysiology of metastatic bone disease -- Bone metastases: epidemiology, clinical picture, SREs and prognosis -- Pain in bone metastases: types and mechanisms. II Investigations Of Bone Metastases -- Radiological evaluations: radiography, CT, MRI.-Â{uED63}clear medicine imaging modalities: bone scintigraphy, PET-CT, SPECT.-Â{u2BEE}ne turnover markers -- New omics approaches for bone metastases. III Therapeutic Management.-Â{u1BA1}algesic treatment for bone mets -- Radiotherapy: external beam and radio-surgery -- Radionuclide therapy -- Bisphosphonates -- New targeted therapies for bone metastases -- Chemotherapy and hormone therapy -- HIFU/Radioablation -- Neuropathic bone metastases -- Spinal cord compression and cauda equina compression -- Pathological and impending fracture -- Re-irradiation -- Bone metastases in elderly patients -- Management of metastatic bone disease in the elderly with bisphosphonates and RANKL inhibitors: effectiveness and safety. IV Assesment of Therapeutic Response -- Radiological and nuclear medicine imaging modalities.-Â{u3B29}inical assessment measures -- Outcome measures in bone metastases clinical trials -- Quality of life in patients suffering from metastatic skeletal disease. V Cost of Managing Metastatic Bone Disease -- Cost effectiveness of treatment modalities for bone metastases -- Index.
520	3		_aThe second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, asignarmaterias, EBSPRINGER,
650	2	7	_aCiencias biomédicas _0 _2embne _9143729
650		7	_aMetástasis óseas _0(OCoLC)835963 _2embne _0 _9677786
700	1		_aChow, Edward _eeditor literario _986265 _0Local
700	1		_aKardamakis, Dimitrios _eeditor literario _986266 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-7569-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12825050 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h0
945			_aRC280.B6 V377 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11554265 _z06-04-17
999			_c76887 _d76887 _x1