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007			cr nn 008mamaa
008			130702s2013 ne | s |||| 0|eng d
020			_a9789400768895
024	7		_a10.1007/978-94-007-6889-5 _2doi
040			_aES-MaUEC
050		4	_aQH603.P47 _bD457 2013 EB
082	0	4	_a610
100	1		_aDel Río, Luis A. _eeditor _0Local _986177
245	1	0	_aPeroxisomes and their Key Role in Cellular Signaling and Metabolism _cedited by Luis A. del Río
260			_aDordrecht, Netherlands _bSpringer _c2013
300			_a1 recurso en línea (XII, 350 p.) _b60 ilustraciones, 48 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aSubcellular Biochemistry _x0306-0225 _v69
505	0		_aPeroxisome interactions and cross-talk with other subcellular compartments in animal cells -- Peroxisomes in human health and disease: metabolic pathways, metabolite transport, interplay with other organelles and signal transduction -- Aging, age-related diseases and peroxisomes -- Peroxisomes and the antiviral responses of mammalian cells -- Peroxisome proliferator-activated receptor-α signaling in hepatocarcinogenesis -- Involvement of human peroxisomes in biosynthesis and signaling of steroid and peptide hormones -- Peroxisome Ca2+ homeostasis in animal and plant cells -- The versatility of peroxisome function in filamentous fungi -- Essential roles of peroxisomally produced and metabolized biomolecules inÂ{u2967}ulating yeast longevity -- Metabolite transporters of the plant peroxisomal membrane - known and unknown -- Peroxisomes and photomorphogenesis -- Biosynthesis of vitamin K1 (phylloquinone) by plant peroxisomesÂ{u1BA4} its integration into signaling molecule synthesis pathways -- Role of peroxisomes as a source of reactive oxygen species (ROS) signaling molecules -- Peroxisomes as a source of auxin signaling molecules -- Peroxisomes as cell generators of reactive nitrogen species (RNS) signal molecules -- Role of plant peroxisomes in the production of jasmonic acid-based signals -- Role of plant peroxisomes in protection against herbivores -- Function of Peroxisomes in Plant-Pathogen Interactions.
520			_aPeroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism. Today it is known that fatty acid β-oxidation is a general feature of virtually all types of peroxisomes, but in higher eukaryotes, including humans, peroxisomes catalyze ether phospholipids biosynthesis, fatty acid α-oxidation, and glyoxylate detoxification, and in humans peroxisomes are associated with several important genetic diseases. Among the different new roles for human peroxisomes discovered in recent years are antiviral innate immunity, peptide hormone metabolism, brain aging and Alzheimerâ€{u3824}isease, and age-related diseases. In fungi, new findings have broadened the number of secondary metabolites that are synthesized in peroxisomes, such as antibiotics and several toxins, and have evidenced their involvement in biotin biosynthesis, fungal development and plant pathogenesis. In plants, peroxisomes carry out different functions, apart from fatty acid β-oxidation, mainly including photorespiration, metabolism of reactive oxygen, nitrogen and sulfur species, photomorphogenesis, biosynthesis of phytohormones, senescence, and defense against pathogens and hervibores. Two important characteristics of peroxisomes are their metabolic plasticity and capacity of sharing metabolic pathways with other cell compartments. In recent years, a function for peroxisomes as key centers of the cellular-signaling apparatus which could influence the regulatory network of the cell has been postulated. The diverse key physiological functions that have been demonstrated for peroxisomes from different origins strongly indicate the interest of studying the role of peroxisomes as a cellular source of different signaling molecules. This book presents recent advances in the function and metabolism of peroxisomes from human, animal, fungal and plant origin and their metabolic interconnection with other cell compartments, showing the central role played by peroxisomes as cell generators of different signaling molecules involved in distinct processes of high physiological importance.
650		7	_9430647 _aProteómica _2embne
650		7	_aCitología _2embne _9139477
710	2		_aSpringerLink (Online service) _0Local _9106996
830		0	_aSubcellular Biochemistry _x0306-0225 _v69 _9133378
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-6889-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12824562 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQH603.P47 D457 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11553777 _z06-04-17
988			_aEBOOK, EBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h0