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008			130702s2013 ne | s |||| 0|eng d
020			_a9789400768666
024	7		_a10.1007/978-94-007-6866-6 _2doi
040			_dES-MaUEC
050		4	_aRC254.6 _bR453 2013
100	1		_aReichle, Albrecht. _eeditor literario _986176 _0Local
245	1	0	_aEvolution-adjusted Tumor Pathophysiology: : _bThe Novel Language of Tumor Biology _cedited by Albrecht Reichle.
260			_aDordrecht, Netherlands _bSpringer International Publishing _c2013
300			_a1 recurso en línea (X, 453 p.) _b95 ilustraciones, 87 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aPreface.-IÂ{u9BB4}troduction.-Communication â{u0825}volution â{u0830}athophysiology: An endogenous conjunction â{u026E}stead of an introduction.-II Combined modularized therapies for metastatic tumors: Pointing to centralÂ{u0CAF}blems of communication among â€s̃ystems participatorsâ€{u0A6E} tumors -- Applied systems biology for the control of metastatic cancer: Therapeutic top-down strategy for targeting the tumorsâ€{u0BAF}rmativity -- Targeting the proangiogenic network in angiosarcomas: Biomodulatory therapy.-Â{uCBEE}ng-term results of combined modularized, immune-modulatory, angiostatic, and antiinflammatory therapy in systemically pre-treated multi-systems Langerhans cell histiocytosis.-Â{u2964}irecting and modulating rationalizations of tumor-immanent normative functions in castration-resistant prostate ancer.-III Social engineering: Biomodulation, either endogenously initiated or by implementation of non-normative boundary conditions -- Non-hierarchically organized operations in malignancies: Stromal dysfunction induces hematopoetic malignancies.-Â{u2A6F}omodulatory therapy approaches in renal clear cell carcinoma: A perspective.-Â{u0CAF}teome analysis identified the PPARc ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.IVÂ{u2820} The tumorsâ€{u0BAF}rmativity: Reconstructing and operationalizing startingÂ{u2830}points for an evolution theory.-Â{u4A25} philosophical quest of a cancer cell: Redefining existentialism.-Â{u4A25} tumorâ€{u382E}ormativity: Normative structures, action norms and decision maxims as therapeutic targets for tumor therapy.-Â{u3CA9}iticizable claims for the validity of communication acts in biological systems: Therapeutic implications in cancer.-VÂ{u5DAF}olution theory.-Â{u5DAF}olution theory: Its practical relevance for understanding tumorÂ{u4976}elopment and specifying tumor therapy -- Modularity, subjectivity, intersubjectivity and normativity: Clinically applicable operative benchmarks -- Turning upside down the mode of science to emphasize and harness the impact of environmental communicative events.Â{u6242}{u2820} From genome- or organ-centric to rationalization-centric systematization ofÂ{u4D6D}ors -- Purposive-rational tumor therapy: Exploiting the tumorâ€{u3822}€l̃iving worldâ€{u2826}or diversifying, specifying and personalizing tumor therapy -- Including rationalizations of tumor-associated normative notions inÂ{u0874}hophysiologic considerations: Communication-theoretical implications.-VIIÂ{u2812}Reconstruction of tumor-immanent normative functions, structures and decision maxims (hubs).-Â{u2CA9}idging a diagnostic and therapeutic gap: Selecting, assessing and categorizing tumor-associated normative notions.-Â{u0972}sonalizing tumor pathophysiology by diagnosing developmental problems in tumors with imaging techniques -- Biologic memory: Induction by metronomically administered combined modularized therapy.-Â{u6249}IÂ{u4A25} tool of rationalizations constituting tumor-associated normativeÂ{uEBF4}ions:Â{u4A25} non-genomic counterpart of the tumor genome and therefore,Â{u1BA0}important therapeutic target for diversifying palliative care -- Diversifying and specifying palliative care for patients with metastatic cancer by therapeutic implementation of non-normative boundary conditions -- Targeting a hallmark of cancer: Simultaneous inflammation and tumor control for palliative care in metastatic cancer.-IXÂ{u03AF}vel clinical and pharmaceutical technology for bioengineering tumorÂ{u2973}ponse.-Â{u3BED}mbined modularized tumor therapy â{u0834}umor biology â{u0821}nd prognostic factors: Bioengineering tumor response.-X Objectifying the systems objectsâ€{u0CF5}bjectivity in biological systems: A novel reification of the scientific picture about the â€õbjectiveâ€{u0DEF}rld -- The systems objectsâ€{u0CF5}bjectivity as scientific object. Index.
520			_aCombined modularized therapies for metastatic cancer are pointing to central problems of communication among â€s̃ystems participatorsâ€{uE801} communication theory explains 'social engineering', endogenously induced or by implementing non-normative boundary conditions. Evolution-adjusted tumor pathophysiology is borne by an evolution theory, which contrasts narrative evolution histories. The tool of rationalizations constituting the tumor's normativity (inflammation, immune response etc.) represents the non-genomic counterpart of the tumor genome and should be additionally assessed during tumor staging. Evolution-adjusted tumor pathophysiology allows implementing applied systems biology, a novel clinical and pharmaceutical technology for bioengineering tumor response and personalizing tumor therapy. Combined modularized therapy, evolution-adjusted tumor pathophysiology, and â€ũniversalâ€{u08A9}omarkers concertedly address genetically based tumor heterogeneity.
650		7	_2embne _9161127 _aTecnología farmacéutica
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-6866-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12824549 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aRC254.6 R453 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11553753 _z06-04-17
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