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020			_a9789400765917
024	7		_a10.1007/978-94-007-6591-7 _2doi
040			_aES-MaUEC
050		4	_aRC281.C4 _bP43 2013 EB
082	0	4	_a614.5999
700	1		_aHayat, M. A. _eeditor literario. _0Local _1http://viaf.org/viaf/95340536 _986068
245	0	0	_aPediatric Cancer, Volume 4 : _bDiagnosis, Therapy, and Prognosis _cedited by M.A. Hayat.
264		1	_aDordrecht, Netherlands _bSpringer _c2013
300			_a1 recurso en línea (XXXVI, 346 páginas) _b55 ilustraciones, 32 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aPediatric Cancer, Diagnosis, Therapy, and Prognosis _x2211-7997 _v4
505	0		_aPreface.Â{u9B82}Â{uE975}uroblastoma -- Pediatric neuroblastoma: use of hypermethylation of apoptotic genes as a prognostic factor -- Mycn nonamplified neuroblastoma: detection of tumor-derived cell-free dna in serum for predicting prognosis of neuroblastoma.-Â{u2820} Neuroblastoma: role of mdm2 and snp309 as markers -- Role of pi3k inhibitors in sensitizing neuroblastoma cells to apoptosis.-Â{u2802}Â{u2820} Regulation of neuroblastoma cell differentiation by retinoic acid: role of alternative splicing and micro-rnas.-Â{uE975}uroblastoma: role of activated leukocyte cell adhesion molecule.-Â{uE975}uroblastoma: inhibition by alu-like rna -- Children with high risk neuroblastoma: prophylactic and therapeutic treatment with docosahexaenoic acid. II. Medulloblastoma.-Â{uFDA5}erview of treatment of pediatric medulloblastoma.-Â{u5DA5}ent-free survival of children with average-risk medulloblastoma: treatment with craniospinal radiation followed by adjuvant chemotherapy.III. Leukemia -- Risk of childhood acute lymphoblastic leukemia: identification of inherited susceptibility.-ÂХdiatric acute lymphoblastic leukemia: role of bim protein in prednisolone-induced apoptosis.-Â{u9BA6}fectious complications of antineoplastic chemotherapy in children with acute leukemia or solid tumors -- Pediatric leukemia of natural killer cells: diagnosis and multi-agent chemotherapy. IV. Lymphoma -- Pediatric lymphoma patients: cytomegalovirus infection.-Â{u4A61}agnosis of bone marrow involvement in pediatric lymphoma patients: fdg pet/ct versus bone marrow biopsy.-Survivors of childhood hodgkinâ€{u3824}isease after treatment: subsequent solid tumor malignancies based on gender and radiation dose.V. Rhabdoid.-Â{u5872}rly childhood paraspinal atypical teratoid/rhabdoid tumor:failure of standard treatments -- Cerebral tumor with rhabdoid features -- Atypical teratoid/rhabdoid tumor of the pineal region: diagnosis. VI. Sarcoma -- Ewingâ€{u3833}arcoma family of tumors: targeting molecular pathways and the race for a cure -- Ewingâ€{u3833}arcoma: current concepts in chemotherapy and surgical control -- Pediatric epithelioid finger sarcoma: diagnosis and treatment.VII. Miscellaneous tumors.-Â{u4A61}agnosis and prognosis of pediatric patients with adrenocortical tumors -- Supratentorial primitive neuroectodermal tumor: therapy -- Giant pediatric midline tumors of the posterior fossa: surgery using combined transventricular and supracerebellar approach.-Â{u0964}iatric gastrointestinal stromal tumor: pathology,genetics, and therapy.-Â{u0964}iatric pituitary adenomas: germline genetic defects.-Â{u0964}iatric ependymomas: role of methylation -- Pediatric intramedullary cavernoma: surgical treatment erwin cornips and mariel ter laak-poort -- Pediatric patients with bone malignancy: therapeutic options -- Late and acute effects of pediatric cancer therapy on the oral cavity -- Air embolism in a pediatric patient: a very rare complication of endoscopic retrograde cholangiopancreatography -- Index.Â{uE000}
520			_aThis entry in the series Pediatric Cancer offers comprehensive information on a variety of cancers, concentrating on brain tumors, the most common solid tumors and the leading cause of cancer-related mortality in children. The contents are organized in seven sections: Neuroblastoma, Medulloblastoma, Leukemia, Lymphoma, Rhabdoid, Sarcoma and Miscellaneous Tumors. Coverage includes pediatric medulloblastoma, and treatments including craniospinal radiation followed by adjuvant chemotherapy. The contributors explain diagnosis and chemotherapy of children with acute lymphoblastic leukemia, and diagnosis of bone marrow involvement in pediatric lymphoma patients. Ewingâ€{u3833}arcoma, a highly malignant connective tissue neoplasm formed by the proliferation of mesenchymal cells, receives extensive coverage, including targeting of molecular pathways and chemotherapy and surgical treatment. The roles of apoptotic genes, MYCN gene, MDM2, and SNP309, P13K inhibitors, alternative splicing and microRNAs, activated leukocyte cell adhesion molecule and inhibition by alu-like RNA in neuroblastoma are discussed in detail. The book explores the molecular genetics, diagnosis, prognosis and therapy of the atypical teratoid/rhabdoid tumor (AT/RT). Among the most common malignant neoplasms in children, AT/RT exhibits similarities with other CNS tumors, which can lead to misclassification, as pointed out in the book. The contributors discuss diagnosis of AT/RT type using imaging technology, and describe new strategies, including intensive multimodal therapy and high dose chemotherapy with autologous stem cell transplantation that have shown improved outcomes. Coverage of therapies includes total resection followed by aggressive chemotherapy and radiation. Discussion includes diagnosis and treatment of other pediatric tumors including adrenocortical tumors, supratentorial primitive neuroectodermal tumors, giant midline tumors, gastrointestinal stromal tumors, ependymomas and intramedullary cavernoma. Pediatric Cancer: Diagnosis, Therapy and Prognosis, Volume 4 includes contributions by ninety-one contributors - oncologists, neurosurgeons, physicians, research scientists and pathologists - representing thirteen countries. The editor, M.A. Hayat, is a Distinguished Professor in the Department of Biological Sciences at Kean University, Union, New Jersey, USA.
650		7	_aOncología pediátrica _9157455
650		7	_aCáncer _xInvestigación _2embne _9182523
710	2		_aSpringerLink (Online service) _0Local _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-6591-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12824379 _b10-10-17 _c01-10-14
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988	0	0	_aEBOOK, EBSPRINGER, GOBI_sep2018
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