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_aQR188.6 _b.T864 2013 EB |
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| 082 | 0 | 4 | _a614.5999 |
| 245 | 0 | 4 |
_aThe tumor Immunoenvironment _cedited by Michael R. Shurin, Viktor Umansky, Anatoli Malyguine |
| 260 |
_aDordrecht, Netherlands _bSpringer _c2013 |
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| 300 |
_a1 recurso en línea (XVI, 745 p.) _b51 ilustraciones |
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| 336 |
_aTexto (visual) _btxt _2rdacontent |
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| 337 |
_aelectrónico _bc _2rdamedia |
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| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 520 | _aInteraction between malignant cells and their surrounding tissue plays a crucial role in tumor growth, invasiveness and spreading to the distant organs. New findings provide evidence of a principal importance of the immune cells for controlling this interaction and orchestrating multiple events in the tumor microenvironment. The balance between immune cells that support tumor progression and immune cells that sustain tumor-controlling immune surveillance is tightly regulated by various factors originated from both the malignant and non-cancerous cells in the tumor microenvironment. Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor ImmunoEnvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development. The main goal of this publication is to provide an overview of the current knowledge on the complex and unique role of the immune system, tumor-associated inflammation and tumor-mediated immunomodulation in cancer progression in a way that allows understanding the logistics of cellular and molecular interactions in the tumor lesions. Moreover, it is discussed how these interactions evolve during cancer progression and in response to different kinds of anticancer therapy. It is anticipated that the book will attract many researchers and clinicians in the field of basic and applied tumor immunobiology and open new opportunities for collaborative programs aiming at the development of effective and feasible therapeutic approaches to cancer treatment. | ||
| 942 |
_2lcc _cLE |
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| 988 | _aEBOOK, EBSPRINGER | ||
| 650 | 7 |
_aTumores _xAspectos inmunológicos _9207056 _0comprobar BNE19930467771 _2embne |
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| 700 | 1 |
_aShurin, Michael R. _eeditor literario _986115 _0Local |
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| 700 | 1 |
_aUmansky, Viktor _eeditor literario _986116 _0Local |
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| 700 | 1 |
_aMalyguine, Anatoli _eeditor literario _986117 _0Local |
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| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-6217-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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_a.b12824161 _b10-10-17 _c01-10-14 |
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