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008			130109s2013 ne | s |||| 0|eng d
020			_a9789400759435
024	7		_a10.1007/978-94-007-5943-5 _2doi
040			_dES-MaUEC
050		4	_aQP34.5 _bM359 2013
100	1		_aMalyshev, Igor. _986101 _0Local
245	1	0	_aImmunity, Tumors and Aging : _bThe Role of HSP70 _cby Igor Malyshev.
260			_aDordrecht, Netherlands _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XI, 141 p.) _b48 ilustraciones, 46 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aSpringerBriefs in Biochemistry and Molecular Biology _x2211-9353 _v6
505	0		_aForward -- Introduction -- 1 A General Description of HSPs, The Molecular Structure of HSP70, The HSP70 Cycle -- 2 HSP70 Functions In Normal Cells -- 3 HSP70 IN A Damaged Cells -- 4 Mechanisms Of Activation And Inactivation Of HSP70 Synthesis -- 5 HSP70 In The Immune Responses -- 6 HSP70 in Carcinogenesis -- 7 HSP70 In Aging -- 8 The Role Of HSP70 in Protection of (a) The Brain In Alzheimerâ€{u3804}isease, and (b) The Heart -- Index.
520			_aThe book is dedicated to the topical area of biology and medicine and the role of stress proteins HSP70 in the regulation of intracellular protein homeostasis, signaling transduction and cell protection. The book is divided into chapters, which describe the discovery of HSP70 and its molecular structure, the mechanism of the synthesis and function in normal and damaged cells, examine the role of HSP70 in immunity, cancerogenesis, aging, Alzheimer's disease and cardiosurgery. In this book, the author looks at HSP70 as a factor which prevents the transformation of homeostasis mechanisms of intracellular proteins into a link in the pathogenesis of a disease.
650		7	_2embne _aFisiología humana _9140024
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-5943-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12824008 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQP34.5 M359 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11553212 _z06-04-17
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