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008			130228s2013 ne | s |||| 0|eng d
020			_a9789400758186
024	7		_a10.1007/978-94-007-5818-6 _2doi
040			_dES-MaUEC
050		4	_aQH596 _b.O339 2013
100	1		_aO'Day, Danton H. _eeditor literario _986083 _0Local
245	1	0	_aProteins of the Nucleolus : _bRegulation, Translocation, & Biomedical Functions _cedited by Danton H O'Day, Andrew Catalano.
260			_aDordrecht, Netherlands _bSpringer International Publishing _c2013
300			_a1 recurso en línea (VI, 371 p.) _b53 ilustraciones, 22 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aPart IÂ{u9BB4}troduction.-Â{u3A20} 1 Proteins of the nucleolus -- Part IIÂ{u2814}The nucleolus and nucleolar proteins -- Ch 2Â{u6D6E}nctional consequences of nuclear and nucleolar architecture.-Âè 3Â{u210E}A and nucleologenesis in Drosophila.-Â{u3A20} 4Â{u4A25} nucleolus of Dictyostelium and other lower eukaryotes -- Ch 5 Human rDNA genes -- Ch 6 Chromatin organization and the mammalian nucleolus -- Ch 7 Chaperones and multitasking proteins in the nucleolus -- Ch 8 Nucleolar localization/retention signals -- Ch 9 Nucleolar transport of putative GTPase GNL1 and related proteins -- Ch 10 Nucleolar protein anchoring and translocation -- Ch 11 The nucleolus as a stress response organelle -- Ch 12 The nucleolar aspect of breast cancer -- Ch 13 Cysteine proteinase inhibitors in the nucleus and nucleolus in activated macrophages -- Ch 14 Nucleolar proteins and cancer -- Ch 15 Nucleolar transplantation and human embryogenesis -- Part V Conclusions -- Ch 16 The nucleolus from its formation to the future.
520			_aThis book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer. This book also brings together work from several different species, from human to Drosophila to Dictyostelium and other eukaryotic microbes. The final chapter summarizes some of the issues brought up in the various chapters with a view to future research. This book supports the continued emergence of the nucleolus as a dynamic intranuclear region that oversees a vast diversity of events.
650		7	_2embne _aCitología _9139477
700	1		_aCatalano, Andrew _eeditor literario _986084 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-5818-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12823880 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQH596 .O339 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11553091 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h0