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020 _a9789400757875
024 7 _a10.1007/978-94-007-5787-5
_2doi
040 _cES-MaUEC
050 4 _aQP177
_b.J356 2013
100 1 _aJakob, Ursula
_eeditor literario
_0Local
_986077
245 1 0 _aOxidative Stress and Redox Regulation
_cedited by Ursula Jakob, Dana Reichmann.
260 _aDordrecht, Netherlands
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (X, 483 p.)
_b72 ilustraciones, 44 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aChapter 1 The Chemistry of Thiol Oxidation and Detection -- Chapter 2 Radical Scavenging by Thiols and the Fate of Thiyl Radicals -- Chapter 3 Redox Homeostasis -- Chapter 4 Sulfenic Acids and Peroxiredoxins in Oxidant Defense and Signaling -- Chapter 5 Â{u6B35}uorescent imaging of redox species in multicellular organisms -- Chapter 6 Redox Proteomics -- Chapter 7 Computational redox biology: methods and applications -- Chapter 8 Â{u2964}ox regulation in plants: Glutathione and “Redoxinâ€{u0CA5}lated families -- Chapter 9 Â{u0CAF}karyotic Redox Switches -- Chapter 10Â{u2820} Combating Oxidative/Nitrosative Stress with Electrophilic Counterattack Strategies -- Chapter 11 Reactive Oxygen Species, Kinase Signaling, and Redox Regulation of Epigenetics -- Chapter 12 Redox regulation of stem cell function -- Chapter 13 Oxidative Stress in Infectious Diseases -- Chapter 14 Oxidative Stress in Aging -- Chapter 15 Oxidative Stress in Cancer -- Chapter 16Â{u2964}ox Pathways as a Platform in Drug Development.
520 _aMany physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
650 7 _2embne
_9139861
_aProteínas
_xMetabolismo
700 1 _aReichmann, Dana
_eeditor literario
_986078
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-5787-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12823831
_b10-10-17
_c01-10-14
942 _2lcc
_cLE
945 _aQP177 .J356 2013 EB
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