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007			cr nn 008mamaa
008			120809s2013 ne a s 001 0 eng d
020			_a9789400747197
024	7		_a10.1007/978-94-007-4719-7 _2doi
040			_aES-MaUEC
050		4	_aRC280.B7 _bG55 2013 EB
082	0	4	_a610
245	0	0	_aGlioma Signaling _cedited by Jolanta Barańska
260			_aDordrecht, Netherlands _bSpringer International Publishing _c2013
300			_a1 recurso en línea (X, 227 p.) _b39 ilustraciones, 27 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v986
505	0		_tIntroduction to Purinergic Signalling in the Brain / _rGeoffrey Burnstock -- _tAdenosine Signaling in Glioma Cells / _rStefania Ceruti and Maria P. Abbracchio -- _tCross-Talk in Nucleotide Signaling in Glioma C6 Cells / _rDorota Wypych and Jolanta Barańska -- _tCalcium Signaling in Glioma Cells -- The Role of Nucleotide Receptors / _rDorota Wypych and Paweł Pomorski -- _tPurinergic Signaling in Glioma Progression / _rElizandra Braganhol, Márcia Rosângela Wink, Guido Lenz and Ana Maria Oliveira Battastini -- _tCytoskeleton and Nucleotide Signaling in Glioma C6 Cells / _rWanda Kłopocka, Jarosław Korczyński and Paweł Pomorski -- _tSignaling Determinants of Glioma Cell Invasion / _rAneta Kwiatkowska and Marc Symons -- _tReceptor Tyrosine Kinases: Principles and Functions in Glioma Invasion / _rMitsutoshi Nakada, Daisuke Kita, Lei Teng, Ilya V. Pyko and Takuya Watanabe, et al. -- _tTGF Beta Signaling and Its Role in Glioma Pathogenesis / _rBozena Kaminska, Marta Kocyk and Magdalena Kijewska -- _tSTAT Signaling in Glioma Cells / _rKarolina Swiatek-Machado and Bozena Kaminska -- _tCannabinoid Signaling in Glioma Cells / _rAleksandra Ellert-Miklaszewska, Iwona Ciechomska and Bozena Kaminska
520	3		_aGliomas, developing in the brain from the transformed glial cells, are a very special kind of tumors, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. Glioma Signaling is a text reference on cellular signaling processes regulating gliomas physiology and invasiveness. The first half of the book is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides. The remaining chapters deal with the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration, cellular growth, progression and invasion, as well as presents perspectives concerning potential targets for glioma therapy.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aCerebro _xTumores _9214753 _0comprobar BNE19932355375 _2embne
650		7	_aGlioma _9144370 _0comprobar BNE19912605003 _2embne
650		7	_aSistema nervioso _xTumores _9195880 _0comprobar BNE19923517286 _2embne
700	1		_aBarańska, Jolanta _eeditor literario _986044 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-4719-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9789400747197
907			_a.b12823636 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b18-07-17 _cm _dz _ea _feng _gne _h0
945			_aRC280 .B7 G55 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11552840 _z06-04-17
999			_c76745 _d76745 _x1