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020			_a9789400746947
040			_aES-MaUEC
050		4	_aQR188.6 _b.T863 2013 EB
082	0	4	_a610
245	0	0	_aTumor Ablation : _beffects on Systemic and Local Anti-Tumor Immunity and on Other Tumor-Microenvironment Interactions _cedited by Yona Keisari
260			_aDordrecht, Netherlands _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XII, 156 p.)
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aThe Tumor Microenvironment _v5
520			_aThe growing knowledge on tumor-immune response interactions and on the tumor microenvironment did not translate so far into better control of cancer by anti-tumor vaccination. The percentage of patients who benefited from vaccination strategies is still too small to justify their general use. It is the aim of this book to present an alternative to the conventional approach of developing injected tumor vaccines to activate anti-tumor immunity, which will fight cancer. It is argued that in situ tumor ablation (destruction) that involves tumor antigen release; cross presentation and the release of danger associated molecular patterns (DAMPs) can make the tumor its own cellular vaccine. Tumor ablation methods using chemicals, radiation, photodynamic therapy, cryoablation, high-temperature, radiofrequency, high intensity focused ultrasound, and electric-based ablation have been developed for focal tumors. In this book experts will deal with two main topics: I. What are the principles of the various ablation modalities, and II. How each method affects the tumor cells and their microenvironment, and how these effects are responsible for the induction of specific anti-tumor immunity. The aims of this book are thus: 1. Familiarize the readers with various methods of in situ tumor ablation. 2. Review the literature and stimulate comparisons on the efficacy of different ablation methods for the treatment of tumors of different histotypes. 3. Review the literature on the effects of various ablation methods on systemic and local anti tumor immunity and on other manifestations of the interactions of tumors with their microenvironment. 4. Stimulate comparative studies on the immunostimulatory effects of different ablation modalities.
650		7	_aTumores _xAspectos inmunológicos _9207056 _0comprobar BNE19930467771 _2embne
700	1		_aKeisari, Yona _xeditor literario _9133379 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-4694-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9789400746947
907			_a.b12823612 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQR188.6 .T863 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11552827 _z06-04-17
988			_aEBOOK, EBSPRINGERrevisando
998			_am _a_alco _a_vill _b28-04-17 _cm _dz _ef _feng _gne _h0