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008			130411s2013 ne a s 001 0 eng d
020			_a9789400746671
024	7		_a10.1007/978-94-007-4667-1 _2doi
040			_aES-MaUEC
050		4	_aQP551 _b.M33 2013 EB
082	0	4	_a610
100	1		_aMacario, Alberto J. L. _0n 84125933 _986037 _0Local
245	1	4	_aThe Chaperonopathies : _bDiseases with Defective Molecular Chaperones _cby Alberto J. L. Macario, Everly Conway de Macario, Francesco Cappello
264		1	_aDordrecht, Netherlands _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XVI, 116 p.) _b26 ilustraciones, 23 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aSpringerBriefs in Biochemistry and Molecular Biology _x2211-9353
505	0		_aOverview and book plan -- Chaperones: General characteristics and classifications -- The chaperonopathies: classification, mechanisms, structural features -- Structural and hereditary chaperonopathies: mutation -- Other genetic chaperonopathies -- Acquired chaperonopathies -- Other types of chaperonopathies -- Impact of chaperonopathies in protein homeostasis and beyond -- Extracellular chaperones.
520	3		_aMemory lapses and occasional incoherent behavior, or intestinal cramps with diarrhea, or protracted cough with low fever, or cardiovascular syndromes, or changes in the pattern of movement of the lower limps, can be signs of an incipient chaperonopathy. Yet many physicians do not know this. Most health care professionals are unfamiliar with chaperonopathies. Clinicians do not look for them because they are unaware of them. Pathologists and clinical biochemists are unprepared to test specimens to detect chaperonopathies. Despite the large amount of information available in the literature, textbooks tend to ignore chaperonopathies. Because of the lack of systematic information in textbooks and courses, chaperonopathies are invisible to practitioners and clinical researchers. This book aims to correct this situation by providing pertinent information in an orderly manner so as to prompt the reader to look for chaperonopathies in patients and seek more information about them. The book serves as an alert signal and as a primer.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aProteínas _0comprobar BNE19900977845 _2embne _9139861
650		7	_aBioquímica _0comprobar BNE19900962333 _2embne _9138639
700	1		_aConway de Macario, Everly _0n 84125935 _986038 _0Local
700	1		_aCappello, Francesco _0n 2013187740 _986039 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-4667-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9789400746671
907			_a.b12823594 _b19-10-17 _c01-10-14
998			_am _a_alco _a_vill _b19-10-17 _cm _dz _ei _feng _gne _h4
945			_aQP551 .M33 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11552803 _z06-04-17
999			_c76741 _d76741 _x1