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007			cr nn 008mamaa
008			140925s2014 ja | s |||| 0|eng d
020			_a9784431551140
024	7		_a10.1007/978-4-431-55114-0 _2doi
040			_dES-MaUEC
050		4	_aQP535.Z6 _bF853 2014
100	1		_aFukada, Toshiyuki _eeditor literario _0Local _985878
245	1	0	_aZinc Signals in Cellular Functions and Disorders _cedited by Toshiyuki Fukada, Taiho Kambe.
260			_aTokyo _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XII, 343 p.) _b63 ilustraciones, 51 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aForeword -- Preface -- 1 Introduction - “Zinc Signalingâ€{uA814}he Blossoming Field of Zinc Biology (Taiho Kambe) -- 2 Molecular Aspects of Zinc Signals (Wolfgang Maret) -- 3 Zinc Transport Proteins and Zinc Signaling (Taiho Kambe, Tokuji Tsuji, and Kazuhisa Fukue) -- 4 Oxidative Stress and Neuronal Zinc Signaling (Hirokazu Hara and Elias Aizenman) -- 5 Zinc Signaling by “Zinc Waveâ€{u0A0B}eigo Nishida and Satoru Yamasaki) -- 6 The Zinc Sensing Receptor, ZnR/GPR39: Signaling and Significance (Michal Hershfinkel) -- 7 Genetically-Encoded Fluorescent Probes for Intracellular Zn2+ Imaging (Anne M. Hessels and Maarten Merkx) -- 8 Zinc Signal in Brain Functions (Atsushi Takeda) -- 9 The Clinical Implications of Impaired Zinc Signalling in the Brain (Sara M. Hancock, Ashley I. Bush, and Paul A. Adlard) -- 10 Zinc Signals in Immunology (Lothar Rink and Martina Maywald) -- 11 Zinc Signal in Inflammation (Ming-Jie Liu and Daren L. Knoell) -- 12 Zinc Signal in Growth Control and Bone Diseases (Toshiyuki Fukada, Shintaro Hojyo, and Bum-Ho Bin) -- 13 Zinc and its Role in the Pathogenesis of Type 2 Diabetes (Yoshio Fujitani, Motoyuki Tamaki, Ayako Fukunaka, and Hirotaka Watada) -- 14 Zinc Signalling and Cancer (Thirayost Nimmanon and Kathryn M. Taylor) -- 15 Zinc as a Key Meiotic Cell Cycle Regulator in the Mammalian Oocyte (Ru Ya, Emily Que, Thomas V. Oâ€{u886C}loran, and Teresa K. Woodruff) -- BM Future Perspectives (Toshiyuki Fukada) -- Index.
520			_aThis book describes the crucial role of "zinc signals" in biological processes on a molecular and physiological basis, discussingÂ{u6D74}ure directions and questions underlying this unique phenomenon. To accomplish this, a group of worldwide leaders in the field, who have made outstanding contributions, overview zinc signals from a professional standpoint. Zinc plays an indispensable role in various cellular processes. It regulates a great number of protein functions including transcription factors, enzymes, adapters, and growth factors as a structural or catalytic factor or both. Recently, another function of zinc has received extensive interest and attention because of its potential importance as a signaling mediator. Zinc plays a dynamic role as an intracellular and extracellular signaling factor and thus regulates cellular signaling pathways, which enables communication between cells, conversion of extracellular stimuli to intracellular signals, and control of various intracellular events. These functions of zinc have become recognized as “zinc signals,â€{u0DE8}ich play critical roles in physiology, and therefore their imbalance can cause a variety of problems with regard to human health. Because the notion of zinc signals is quite new and no integrative review books focusing on them have yet been published, we believe this book will provide very timely information on the subject and thus should be of importance and interest to a wide range of readers.
650		7	_2embne _9138487 _aFisiología
650		7	_2embne _aCélulas _9139475
700	1		_aKambe, Taiho _eeditor literario _985879 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-55114-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12822759 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQP535.Z6 F853 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11551963 _z06-04-17
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