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007			cr nn 008mamaa
008			100301s2006 sz | s |||| 0|eng d
020			_a9783764374426
024	7		_a10.1007/3-7643-7442-X _2doi
040			_dES-MaUEC
050		4	_aQR185.8.L9 _bB336 2006
100	1		_aBadolato, Raffaele _eeditor literario _0Local _985766
245	1	0	_aLymphocyte Trafficking in Health and Disease _cedited by Raffaele Badolato, Silvano Sozzani.
260			_aBasel _bSpringer International Publishing _c2006
300			_a1 recurso en línea (X, 253 p.) :
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aProgress in Inflammation Research
505	0		_aLymphocyte trafficking: from immunology paradigms to disease mechanisms -- Lymphocyte trafficking: from immunology paradigms to disease mechanisms -- Physiology of lymphocyte trafficking -- Biology of chemokines -- Lymphocyte-endothelial cell interaction -- Chemokine receptor expression in effector and memory T cell subsets -- Migration of dendritic cell subsets -- Migration of NK cells -- Immunopathology of lymphocyte trafficking -- Lymphocyte trafficking and chemokine receptors during pulmonary disease -- Lymphocyte migration to the brain -- Lymphocyte migration to the kidney -- Leukocyte migration to pancreatic islets: a critical step in the pathogenesis of type 1 diabetes -- Controlling leukocyte trafficking in disease -- Inherited disorders of lymphocyte trafficking -- Leukocyte adhesion deficiency -- Wiskott-Aldrich syndrome as a model of cytoskeleton defects -- From CXCR4 mutations to WHIM syndrome.
520			_aSince the discovery of chemokines and of chemokine receptors it has become evident that expression of chemokines at the site of inflammation may regulate the composition of cellular infiltrate, thereby directing the type of immune response. Recently, the molecular characterization of inherited disorders of immune system, (e.g., Wiskott-Aldrich syndrome, WHIM syndrome, leukocyte adhesion deficiency), which are characterized by cytoskeleton/adhesion defects or by altered response of chemokine receptors has contributed to clarifying the key players of immune response in normal physiology and in disease. This book, which deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention, offers a series of contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease.
650		7	_2embne _aInmunología _9138330
700	1		_aSozzani, Silvano _eeditor literario _985767 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/3-7643-7442-X _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12822334 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQR185.8.L9 B336 2006 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11551549 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gsz _h0