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020 _a9783764373788
024 7 _a10.1007/3-7643-7378-4
_2doi
040 _aES-MaUEC
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050 4 _aRC268.5
_bB546 2006 EB
100 1 _aBignold, Leon P.
_eeditor.
_985752
_0Local
245 1 0 _aCancer: Cell Structures, Carcinogens and Genomic Instability
_cedited by Leon P. Bignold.
260 _aBasel
_bBirkhÃ{u5CE5}r Basel
_c2006.
300 _a1 recurso en línea (XI, 376 páginas) :
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aExperientia Supplementum
_v96
505 0 _aCancer morphology, carcinogenesis and genetic instability: a background -- Abnormalities of chromatin in tumor cells -- Aneuploidy, stem cells and cancer -- The mode of action of organic carcinogens on cellular structures -- Metal ions and carcinogenesis -- Actions of ultraviolet light on cellular structures -- Actions of radiation on living cells in the “post-bystanderâ€{u0972}a -- Viral carcinogenesis and genomic instability -- Abnormalities of cell structures in tumors: apoptosis in tumors -- Molecular regulation of tumor angiogenesis: mechanisms and therapeutic implications -- Genetic and environmental factors in hereditary predisposition to tumors: a conceptual overview -- Effects of ionizing radiation on cellular structures, induced instability and carcinogenesis -- Genetic instability in human tumors -- Molecular mechanisms of human carcinogenesis -- Mechanisms of abnormal gene expression in tumor cells.
520 3 _aTumors can be induced by a variety of physical and chemical carcinogens. The resulting tumor cells are usually abnormal in their morphology and behavior and transmit their abnormalities to their daughter tumor cells. Most theories of the pathogenesis of tumors suggest that carcinogens in some way cause alterations either of the genomes or of inheritable patterns of gene expression in normal cells, which then cause morphological and behavioral changes. This volume presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells. It includes reviews of cellular targets of known carcinogens, and presents varying viewpoints of how morphological abnormalities and the actions of carcinogens might be related. The volume will be of interest to all those who are involved in cancer research or in the prevention, diagnosis or management of tumors in humans or animals.
650 7 _aCáncer
_xAspectos genéticos
_0(OCoLC)845368
_2embne
_9273952
_0comprobar BNE19900970859
710 2 _aSpringerLink (Online service)
_0Local
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856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/3-7643-7378-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12822243
_b10-10-17
_c01-10-14
942 _2lcc
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945 _aRC268.5 B546 2006 EB
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