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001			76567
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005			20230202102129.0
007			cr nn 008mamaa
008			140708s2014 gw | s |||| 0|eng d
020			_a9783662434925
024	7		_a10.1007/978-3-662-43492-5 _2doi
050		4	_aQR185.8.I56 _bI58 2014 EB
082	0	4	_a616.079
245	0	0	_aInterleukin-10 in Health and Disease _cedited by Simon Fillatreau, Anne O'Garra
260			_aBerlin, Heidelberg _bSpringer International Publishing _c2014
300			_a1 recurso en línea (VIII, 238 p.) _b16 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v380
505	0		_aIL-10 in humans: lessons from the gut, IL-10/IL-10 receptor deficiencies and IL-10 polymorphisms -- Control of intestinal inflammation by interleukin-10 -- Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications -- Interleukin-10-producing B cells and the regulation of immunity -- Pathogen Manipulation of cIL-10 Signaling Pathways: Opportunities for Vaccine Development?- IL-10: achieving balance during persistent viral infection -- The role of microRNAs in the control and mechanism of action of IL-10 -- The regulation of IL-10 expression -- The Molecular Basis of IL-10 Function:From Receptor Structure to the Onset of Signaling -- Role of IL-22 in microbial host defense
520			_aThis volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aInterleuquinas _9165129 _0comprobar BNE20051505382 _2embne
700	1		_aFillatreau, Simon _eeditor literario _985698 _0Local
700	1		_aO'Garra, Anne _eeditor literario _985699 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-662-43492-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783662434925
907			_a.b12821858 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b31-07-17 _cm _dz _eb _feng _ggw _h0
945			_aQR185.8 .I56 I58 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11551069 _z06-04-17
999			_c76567 _d76567 _x1