000			03563nam a22003855i 4500
001			76541
003			ES-MaUEC
005			20230207040228.0
007			cr nn 008mamaa
008			140325s2014 gw s 000 0 eng d
020			_a9783642451065
024	7		_a10.1007/978-3-642-45106-5 _2doi
050		4	_aQP363 _b.N48 2014 EB
082	0	4	_a615
245	0	0	_aNeurotrophic Factors _cedited by Gary R. Lewin, Bruce D. Carter
264		1	_aBerlin, Heidelberg _bSpringer International Publishing _c2014
300			_a1 recurso en línea (VIII, 520 p.) _b37 ilustraciones, 27 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aHandbook of Experimental Pharmacology _x0171-2004 _v220
505	0		_aThe Neurotrophin Family: NGF, BDNF, NT3 and NT4 -- Deciphering Proneurotrophin Actions -- Spatio-Temporal Intracellular Dynamics of Neurotrophins and Their Receptors. Implications for Neurotrophin Signaling and Neuronal Function -- Neurotrophins: Transcription and Translation -- Neurotrophin Receptors: Trk Receptors -- The Biological Functions and Signaling Mechanisms of the p75 Neurotrophin Receptor -- Sortilins in Neurotrophic Factor Signaling -- The Biology of Neurotrophins: Neurotrophins in the Regulation of Cellular Survival and Death -- BDNF and Synaptic Plasticity, Cognitive Function and Dysfunction -- Nerve Growth Factor and Nociception: From Experimental Embryology to New Analgesic Therapy -- Neurotrophins and the Regulation of Energy Balance and Body Weight -- The Biology of Neurotrophins: Cardiovascular Function -- Neurotrophin signalling and transcription programs interactions in the development of somatosensory neurons -- Neurotrophins in Pathological Conditions: Huntington's disease -- Motoneuron Disease -- Neurotrophic Factors in Spinal Cord Injury -- Neurotrophins and Psychiatric Disorders -- Brain Derived Neurotrophic Factor and Rett Syndrome -- Modulation of Neurotrophin Signaling by Monoclonal Antibodies
520	3		_aThis book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington's syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aNeuronas _xFisiología _9217236 _0comprobar BNE19940007478 _2embne
650		7	_aNeurofisiología _0comprobar BNE19912762456 _2embne _9144482
700	1		_aLewin, Gary R. _0nb2014011644 _eeditor literario _948500
700	1		_aCarter, Bruce D. _0nb2014011645 _eeditor literario _948501
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-642-45106-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783642451065
907			_a.b12821597 _b23-10-17 _c01-10-14
998			_am _a_alco _a_vill _b23-10-17 _cm _dz _eu _feng _ggw _h0
945			_aQP363 .N48 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11550806 _z06-04-17
999			_c76541 _d76541 _x1