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001			76519
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005			20230207040227.0
007			cr nn 008mamaa
008			131209s2013 gw s 000 0 eng d
020			_a9783642402326
024	7		_a10.1007/978-3-642-40232-6 _2doi
050		4	_aQR201.T6 _bP38 2013 EB
082	0	4	_a616.9041
245	0	0	_aPathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism _cedited by Jean Pieters, John D. McKinney
260			_aBerlin, Heidelberg _bSpringer International Publishing _c2013
300			_a1 recurso en línea (VIII, 245 p.) _b22 ilustraciones, 11 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v374
505	0		_aGenetic Diversity in Mycobacterium tuberculosis -- DNA Metabolism in Mycobacterial Pathogenesis -- Molecular Biology of Drug Resistance in Mycobacterium tuberculosis -- Antimicrobial Efflux Pumps and Mycobacterium tuberculosis Drug Tolerance: Evolutionary Considerations -- Getting Across the Cell Envelope: Mycobacterial Protein Secretion -- A Single-Cell Perspective on Non-Growing but Metabolically Active (NGMA) Bacteria -- Mycobacterium tuberculosis Metabolism and Host Interaction: Mysteries and Paradoxes -- Surviving the Macrophage: Tools and Tricks Employed by Mycobacterium tuberculosis -- Host-Pathogen Interactions During Mycobacterium tuberculosis Infections
520	3		_aMycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of M. tuberculosis in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the hostâ€{u3829}nnate immune defence mechanisms. In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of M. tuberculosis, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aTuberculosis _9140389 _0comprobar BNE19900984506 _2embne
700	1		_aPieters, Jean _eeditor literario _985649 _0Local
700	1		_aMcKinney, John D. _eeditor literario _985650 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-642-40232-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783642402326
907			_a.b12821378 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b04-10-17 _cm _dz _eu _feng _ggw _h0
945			_aQR201.T6 P38 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11550582 _z06-04-17
999			_c76519 _d76519 _x1