000			02832nam a22003615i 4500
001			76516
003			ES-MaUEC
005			20230207040227.0
007			cr nn 008mamaa
008			131004s2014 gw a fs 001 0 eng d
020			_a9783642399688
024	7		_a10.1007/978-3-642-39968-8 _2doi
050		4	_aRM267 _b.A585 2014 EB
082	0	4	_a616.9041
245	0	0	_aAntimicrobials : _bNew and Old Molecules in the Fight Against Multi-resistant Bacteria _cedited by Flavia Marinelli, Olga Genilloud
260			_aBerlin, Heidelberg _bSpringer International Publishing _c2014
300			_a1 recurso en línea (VIII, 364 p.) _b71 ilustraciones, 10 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
520	3		_aReports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the 2arms race3 with resistant pathogens. This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aAntibióticos _9138527 _0comprobar BNE19900960904 _2embne
650		7	_aEnfermedades infecciosas _0comprobar BNE19900959429 _2embne _9138404
700	1		_aMarinelli, Flavia _eeditor literario _985642 _0Local
700	1		_aGenilloud, Olga _eeditor literario _985643 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-642-39968-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783642399688
907			_a.b12821342 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b22-06-17 _cm _dz _ea _feng _ggw _h0
945			_aRM267 .A585 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11550557 _z06-04-17
999			_c76516 _d76516 _x1