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020 _a9783642397967
024 7 _a10.1007/978-3-642-39796-7
_2doi
050 4 _aQP620
_b.N83 2014 EB
082 0 4 _a572.6
245 0 0 _aNucleic Acid Polymerases
_cedited by Katsuhiko S. Murakami, Michael A. Trakselis
260 _aBerlin, Heidelberg
_bSpringer International Publishing
_c2014
300 _a1 recurso en línea (VIII, 342 p.)
_b76 ilustraciones, 53 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aNucleic Acids and Molecular Biology
_x0933-1891
_v30
505 0 _aStructural aspects of mitochondrial ribosome function -- Mechanism and control of protein synthesis in mammalian mitochondria -- Translation in mammalian mitochondria : Order and disorder linked to tRNA and Aminoacyl-tRNA synthetases -- Mitochondrial targeting of RNA and mitochondrial translation in yeast and mammalians -- Mechanisms and control of protein synthesis in yeast mitochondria -- Mitochondrial translation in trypanosomatids -- Translation in mitochondria and apicoplasts in Apicomplexa -- Translation in mitochondria in green alga and higher plants -- Translation in flowering plant chloroplasts -- The chloroplasts as platform for recombinant proteins production
520 3 _aThis book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases such as telomerase, template-independent terminal nucleotidyl transferase and RNA self-replication ribozyme. Although many books cover several different types of polymerases, no book so far has attempted to catalog all nucleic acid polymerases. The goal of this book is to be the top reference work for postgraduate students, postdocs, and principle investigators who study polymerases of all varieties. In other words, this book is for polymerase fans by polymerase fans. Nucleic acid polymerases play a fundamental role in genome replication, maintenance, gene expression and regulation. Throughout evolution these enzymes have been pivotal in transforming life towards RNA self-replicating systems as well as into more stable DNA genomes. These enzymes are generally extremely efficient and accurate in RNA transcription and DNA replication and share common kinetic and structural features. How catalysis can be so amazingly fast without loss of specificity is a question that has intrigued researchers for over 60 years. Certain specialized polymerases that play a critical role in cellular metabolism are used for diverse biotechnological applications and are therefore an essential tool for research
942 _2lcc
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988 _aEBOOK, EBSPRINGERrevisando
650 7 _9140525
_aÁcidos nucleicos
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700 1 _aMurakami, Katsuhiko S.
_eeditor literario
_985638
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700 1 _aTrakselis, Michael A.
_eeditor literario
_985639
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-642-39796-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783642397967
907 _a.b12821329
_b10-10-17
_c01-10-14
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