000			04041nam a22003615i 4500
001			76504
003			ES-MaUEC
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008			131220s2013 gw | s |||| 0|eng d
020			_a9783642389191
040			_aES-MaUEC
050		4	_aQR189 _b.A534 2013 EB
082	0	4	_a616.9101
245	0	0	_aChallenges and Opportunities for Respiratory Syncytial Virus Vaccines _cedited by Larry J. Anderson, Barney S. Graham
260			_aBerlin _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XI, 409 p.) _b38 ilustraciones, 22 il.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v372
505	0		_aRespiratory Syncytial Virus: Virology, Reverse Genetics, and Pathogenesis of Disease -- Clinical and Epidemiologic Features of Respiratory Syncytial Virus -- Influence of Respiratory Syncytial Virus Strain Differences on Pathogenesis and Immunity -- Structure and Function of Respiratory Syncytial Virus Surface Glycoproteins -- Respiratory Syncytial Virus and Reactive Airway Disease -- Human Genetics and Respiratory Syncytial Virus Disease: Current Findings and Future Approaches -- Innate Immune Responses to Respiratory Syncytial Virus Infection -- The Adaptive Immune Response to Respiratory Syncytial Virus -- Respiratory Syncytial Virus Mechanisms to Interfere with Type 1 Interferons -- Host Gene Expression and Respiratory Syncytial Virus Infection -- Consequences of Immature and Senescent Immune Responses for Infection with Respiratory Syncytial Virus -- Respiratory Syncytial Virus Disease:Âвevention and Treatment -- Live-Attenuated Respiratory Syncytial Virus Vaccines -- Subunit and Virus-Like Particle Vaccine Approaches for Respiratory Syncytial Virus -- Gene-Based Vaccine Approaches for Respiratory Syncytial Virus -- Bovine Model of Respiratory Syncytial Virus Infection -- The Cotton Rat S. hispidus Model of Respiratory Syncytial Virus Infection -- The Mouse Model of Respiratory Syncytial Virus Disease -- Human Airway Epithelial Cell Cultures for Modeling Respiratory Syncytial Virus Infection -- Challenges and Opportunities for Respiratory Syncytial Virus Vaccines.
520			_aAlthough respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure. The success of RSV immune prophylaxis and the availability of ever more powerful tools to study the immune response and pathogenesis of disease, combined with the ability to construct a wide variety of vaccines using different vaccine platforms, give us grounds to believe that an RSV vaccine is within reach. This book brings together in one source what is currently known about the virus: its clinical and epidemiologic features; the host response and pathogenesis of the disease; vaccines, vaccine platforms, and treatment; and animal and tissue culture models of RSV infection. It is designed to organize the critical information relevant to RSV vaccine development, facilitate the assimilation of data, and speed progress toward producing a safe and effective vaccine.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aVacunas _0comprobar BNE19900984775 _2embne _9140409
700	1		_aAnderson, Larry J. _eeditor literario _985620 _0Local
700	1		_aGraham, Barney S. _eeditor literario _985621 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-642-38919-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783642389191
907			_a.b12821226 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b05-07-17 _cm _dz _ef _feng _ggw _h0
945			_aQR189 .A534 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11550430 _z06-04-17
999			_c76504 _d76504 _x1