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020 _a9783642368530
050 4 _aR857.N34
_bD53 2013 EB
082 0 4 _a611.01816
245 0 0 _aDNA and RNA Nanobiotechnologies in Medicine: Diagnosis and Treatment of Diseases
_cedited by Volker A. Erdmann, Jan Barciszewski.
260 _aBerlin, Heidelberg
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (VIII, 460 p.)
_b122 ilustraciones, 67 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aRNA Technologies
505 0 _aIntroduction -- RNA Nanotechnology: methods for synthesis, conjugation, assembly and application of RNA nanoparticles -- Adsorption of double-stranded DNA to graphene oxide preventing enzymatic digestion -- Electrogenerated chemiluminescence of conjugated polymer films from patterned electrodes -- Use of RNA structure flexibility data in nanostructure modeling -- Informatic resources for identifying and annotating structural RNA motifs -- A nanostructure made of a bacterial noncoding RNA -- HAPIscreen, a method for high-throughput aptamer identification -- Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA -- Bifacial nucleoside as a surrogate for both T and A in duplex DNA -- Functionally important structural elements of U12 snRNA -- Self-assembling RNA nanorings based on RNAI/II inverse kissing complexes -- Automatic molecular weaving prototyped by using single-stranded DNA -- Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons -- Nanotextured Substrates With Immobilized Aptamers for Cancer Cell Isolation and Cytology -- Targeting cancer with peptide aptamers -- Synthetic, biofunctional nucleic acid-based molecular devices -- Inducible site-selective bottom-up assembly of virus-derived nanotube arrays on RNA-equipped wafers -- Special delivery: targeted therapy with small RNAs, RNAi nanomedicines: challenges and opportunities within the immune system -- Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): Tools for fundamental research, diagnostics, and nanotechnology -- Stabilizing RNA by the sonochemical formation of RNA nanospheres. Sonochemical synthesis of DNA nanospheres -- Nucleic acid based molecular devices -- Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study -- A sol-gel-based microfluidics system enhances the efficiency of RNA aptamer selection -- Hierarchical nanotextured microelectrodes overcome the molecular transport barrier to achieve rapid, direct bacterial detection -- Recent developments in lipid-based pharmaceutical nanocarriers -- Targeted delivery of RNAi therapeutics for cancer therapy -- DNAsomes: Multifunctional DNA-based nanocarriers -- Reversible and Controllable Nanolocomotion of an RNA-Processing Machinery -- Scavenger receptors mediate cellular uptake of polyvalent oligonucleotide-functionalized gold nanoparticles -- A highly sensitive microRNA biosensor based on ruthenium oxide nanoparticle-initiated polymerization of aniline -- Preparation and high-resolution microscopy of gold cluster labeled nucleic acid conjugates and nanodevices -- Kinetically grafting G-quadruplexes onto DNA nanostructures for structure and function encoding via a DNA machine -- Synthesis of glycerol nucleic acid (GNA) phosphoramidite monomers and oligonucleotide polymers -- Cancer immunotherapy and nanomedicine -- RNA nanotechnology: inspired by DNA -- From nanotechnology to nanomedicine: applications to cancer research -- Comparative structural and functional studies of nanoparticle formulations for DNA and siRNA delivery -- Advances in novel drug delivery strategies for breast cancer therapy -- DNA origami: a history and current perspective -- Nanoparticles: a promising modality in the treatment of sarcomas -- Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication -- Recent developments in oligonucleotide conjugation -- In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers -- DNA and carbon nanotubes as medicine -- LHRH-targeted nanoparticles for cancer therapeutics -- Nanoparticle-aptamer conjugates for cancer cell targeting and detection -- Evaluation of targets for ovarian cancer gene silencing therapy: in vitro and in vivo approaches -- Prediction and design of DNA and RNA structures -- siRNA applications in nanomedicine.
520 _aThis book will provide latest insights in the functional potentials of ribonucleic acids in medine and the use of Spiegelmer and Spiegelzyme systems. It will also deal with a new type of delivery systems for cellular targeting.
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGERrevisando
650 7 _aNanotecnología
_0comprobar BNE20011268513
_2embne
_9158453
700 _aErdmann, Volker
_eeditor literario
_0Local
_985268
700 1 _aBarciszewski, Jan
_eeditor literario
_985269
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-642-36853-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783642368530
907 _a.b12820969
_b10-10-17
_c01-10-14
998 _am
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_a_vill
_b16-09-17
_cm
_dz
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_h0
945 _aR857 .N34 D53 2013 EB
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