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020 _a9783642360022
024 7 _a10.1007/978-3-642-36002-2
_2doi
050 4 _aQH506
_b.E96 2013 EB
082 0 4 _a571.6
245 0 0 _aEvolution of Extracellular Matrix
_cedited by Fred W. Keeley, Robert P. Mecham
260 _aBerlin, Heidelberg
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (X, 290 páginas)
_b50 ilustraciones, 23 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aBiology of Extracellular Matrix
_x0887-3224
505 0 _aJosephine C. Adams: Extracellular Matrix Evolution: An Overview -- Hiroshi Wada: Domain Shuffling and the Evolution of Vertebrate Extracellular Matrix -- Jean-Yves Exposito, Claire Lethias: Invertebrate and Vertebrate Collagens -- Fred. W. Keeley: The Evolution of Elastin -- Sacha Jensen, David Yadin, Ian Robertson, Penny Handford: Evolutionary Insights into Fibrillin Structure and Function in the Extracellular Matrix -- Fernando Segade: Molecular Evolution of the Microfibril-associated Proteins: The Fibulins and the MAGPs -- Cristina A. Baratta, Theodore J. Brown, Fahd Al-Dhalaan, Maurice J. Ringuette: Evolution and Function of SPARC and Tenascins: Matricellular Counter-adhesive Glycoproteins with Pleotropic Effects on Angiogenesis and Tissue Fibrosis -- David D. Roberts, William A. Frazier: Thrompospondins and their Receptors: Evolving Functions -- Mark S. Johnson, Jarmo Käpylä, Konstantin Denissiouk, Tomi Airenne, Bhanupratap Singh Chouhan, Jyrki Heino: Evolution of Cell Adhesion to Extracellular Matrix
520 _aThe evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGERrevisando
650 7 _aBiología molecular
_0comprobar BNE19900968373
_2embne
_9139103
650 7 _aCitología
_0comprobar BNE19900972907
_2embne
_9139477
700 1 _aKeeley, Fred W.
_eeditor literario
_985559
_0Local
700 1 _aMecham, Robert P.
_eeditor literario
_985552
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-642-36002-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783642360022
907 _a.b12820805
_b07-11-17
_c01-10-14
998 _am
_a_alco
_a_vill
_b07-11-17
_cm
_dz
_eb
_feng
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_h0
945 _aQH506 .E96 2013 EB
_g1
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