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007			cr nn 008mamaa
008			100301s2006 gw | s |||| 0|eng d
020			_a9783540333975
024	7		_a10.1007/978-3-540-33397-5 _2doi
050		4	_aQR185.8.C45 _bL364 2006
100	1		_aLane, Thomas E. _eeditor. _985415 _0Local
245	1	0	_aChemokines and Viral Infection _cedited by Thomas E. Lane.
260			_aBerlin, Heidelberg _bSpringer Berlin Heidelberg _c2006.
300			_a1 recurso en línea (XI, 157 páginas) _b14 ilustraciones
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v303
505	0		_aFunctional Diversity of Chemokines and Chemokine Receptors in Response to Viral Infection of the Central Nervous System -- Cytokine and Chemokine Networks: Pathways to Antiviral Defense -- Herpes Simplex Virus and the Chemokines That Mediate the Inflammation -- Influence of Proinflammatory Cytokines and Chemokines on the Neuropathogenesis of Oncornavirus and Immunosuppressive Lentivirus Infections -- HIV-1 Coreceptors and Their Inhibitors -- A Viral Conspiracy: Hijacking the Chemokine System Through Virally Encoded Pirated Chemokine Receptors.
520	3		_aThis edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, asignarmaterias, EBSPRINGER,
650	2	4	_9405049 _aMicrobiología médica _0
650		7	_aEnfermedades víricas _0(OCoLC)1167739 _2embne _0 _9413118
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-540-33397-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12819906 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQR185.8.C45 L364 2006 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11549129 _z06-04-17
999			_c76372 _d76372 _x1