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020 _a9783540312659
024 7 _a10.1007/3-540-31265-X
_2doi
040 _bspa
_dES-MaUEC
050 4 _aQH588.S83
_bW638 2006
082 0 4 _a615
100 1 _aWobus, Anna M.
_eeditor.
_985360
_0Local
245 1 0 _aStem Cells
_cedited by Anna M. Wobus, Kenneth R. Boheler.
260 _aBerlin, Heidelberg
_bSpringer Berlin Heidelberg
_c2006.
300 _a1 recurso en línea (XI, 414 p.)
_b53 ilustracionesr.
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aHandbook of Experimental Pharmacology
_x0171-2004
_v174
505 0 _aFactors Involved in Self-Renewal and Pluripotency of Embryonic Stem Cells -- Embryonic Stem Cell-Derived Embryoid Bodies: An In Vitro Model of Eutherian Pregastrulation Development and Early Gastrulation -- Embryonic Stem Cells: A Novel Tool for the Study of Antiangiogenesis and Tumor-Induced Angiogenesis -- Cardiac Repair by Embryonic Stem-Derived Cells -- Cardiomyocytes from Human Embryonic Stem Cells -- Autocrine and Intracrine Signaling for Cardiogenesis in Embryonic Stem Cells: A Clue for the Development of Novel Differentiating Agents -- Therapeutic Potential of Stem Cells in Diabetes -- The Stem Cell Continuum: A New Model of Stem Cell Regulation -- Markers of Adult Tissue-Based Stem Cells -- Designer Cytokines for Human Haematopoietic Progenitor Cell Expansion: Impact for Tissue Regeneration -- Mesenchymal Stem Cells: Isolation, In Vitro Expansion and Characterization -- Neovascularization and Cardiac Repair by Bone Marrow-Derived Stem Cells -- The Potential Use of Myogenic Stem Cells in Regenerative Medicine -- Neural Stem Cells: On Where They Hide, in Which Disguise, and How We May Lure Them Out -- Cell Transplantation for Patients with Parkinsonâ€{u3804}isease -- Postmodern Biology: (Adult) (Stem) Cells Are Plastic, Stochastic, Complex, and Uncertain.
520 _aSigni?cant advances in stem cell research and their potentials for therap- tic applications have attracted the attention of the scienti?c community and captured the imagination of society as a whole. Not so long ago, the study of most stem cells, other than those that regenerated the haematopoietic system, was rather obscure and limited to a relatively small number of researchers and laboratories. The uproar over stem cells really began in 1998 with the s- cessful derivation of pluripotent human embryonic stem (ES) cells by James Thomson and co-workers. This breakthrough and the subsequent generation of specialized human cells in vitro led to a paradigm shift within the sci- ti?c community, which transformed this specialized endeavour from a topic of scienti?c interest to a line of investigation with the potential to generate cells - pable of treating serious ailments, including diabetes, cardiovascular diseases and neurodegenerative disorders. Thus the dawn of regenerative medicine has spawned from the somewhat esoteric study of stem cells. Since 1998, extensive research endeavours have been devoted to the study of both embryonic and adult stem cells. Early reports suggested that adult stem cells had a higher plasticity than previously believed, perhaps even comparable with that demonstrated by embryonic stem cells, but several observations of the so-called transdifferentiation capacity and plasticity of adult stem cells have not been repeated. These reports, however, encouraged on-going debates about the capacity of adult versus embryonic stem cells and their potential use in regenerative medicine.
650 7 _2embne
_aCélulas madre
_9160528
700 1 _aBoheler, Kenneth R.
_eeditor literario
_0Local
_985361
710 2 _aSpringerLink (Online service)
_0Local
_9106996
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/3-540-31265-X
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12819591
_b10-10-17
_c01-10-14
942 _2lcc
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945 _aQH588.S83 W638 2006 EB
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