000			02475nam a22003615i 4500
988			_aEbook_one2one
999			_c76330 _d76330 _x1
001			76330
003			ES-MaUEC
005			20240611040132.0
006			a||||fo|||| 00| 0
007			cr nn 008mamaa
008			100301s2006 gw | s |||| 0|eng d
020			_a9783540305927
024	7		_a10.1007/3-540-30592-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH465 _b2006 EB
100	1		_aSonntag, Clemens. _985340 _1http://viaf.org/viaf/54623662
245	1	0	_aFree-Radical-Induced DNA Damage and Its Repair : _bA Chemical Perspective _cby Clemens Sonntag.
264		1	_aBerlin, Heidelberg _bSpringer International Publishing _c2006.
300			_a1 recurso en línea (XX, 523 páginas) :
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aFormation of Reactive Free Radicals in an Aqueous Environment -- The Hydroxyl Radical -- Hydrogen Atom and Hydrated Electron -- Inorganic Radicals -- Carbon-Centered Radicals -- Heteroatom-Centered Radicals -- Peroxyl Radicals -- Polymer Radicals -- Nucleobases, Nucleosides and Nucleotides -- Polynucleotides and Single-Stranded DNA Fragments -- DNA and Double-Stranded Oligonucleotides -- Methods.
520			_aUnderstanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals have various sources, notably ionizing radiation and oxidative stress. In radiotherapy for cancer and with some anticancer drugs, use is made of cell death by excessive DNA damage. The mechanisms leading to products of free-radical attack which have been studied in models and with small double-stranded DNA fragments are discussed in detail, and the basics of the underlying free-radical chemistry are dealt with in separate chapters.
988			_aEBOOK, EBSPRINGERrevisando, GOBI_sep2018
650		7	_aRadicales libres (Química) _2embne _9148373
650		7	_aADN _2embne _9140806
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/3-540-30592-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b10/2020 _dz _ek