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001			76274
003			ES-MaUEC
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007			cr nn 008mamaa
008			140704s2014 gw s 000 0 eng d
020			_a9783319078274
024	7		_a10.1007/978-3-319-07827-4 _2doi
040			_aES-MaUEC
050		4	_aQP356.2 _b.P36 2014 EB
082	0	4	_a612.8
100	1		_aPandey, Amita _985241 _0Local
245	1	4	_aThe UNC-53-mediated Interactome : _bAnalysis of its Role in the Generation of the C. elegans Connectome _cby Amita Pandey, Girdhar K. Pandey
260			_aCham, Switzerland _bSpringer International Publishing _c2014
300			_a1 recurso en línea (VI, 87 p.) _b15 ilustraciones, 14 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aSpringerBriefs in Neuroscience _x2191-558X
505	0		_aIntroduction -- Guidance molecules required for growth cone migrations of cells and axons -- Mechanism for asymmetric localization of guidance receptors during growth cone migration and outgrowth -- Signaling pathways downstream of the guidance cues and receptors -- Functional characterization of adaptor protein UNC-53 during axon outgrowth and cell migration.
520	3		_aThis book gives an overview of various interactomes involved in dorsal ventral (DV) and anterior posterior (AP) guidance, their mechanisms of action, subcellular localizations, and functional roles. It will provide readers a better understanding of the development of the nervous system, which in turn will help to find cures to various neural and other disorders. In nematodes there are two types of guidance systems, including DV and AP guidance. The signaling process that guides the growth cones along the DV axis has remained intact in both vertebrates and invertebrates. The adaptor protein UNC-53 appears to play a part in migration along the AP axis in both worms and their human homologs. "Neuron Navigators" (NAV) are also involved in nervous system development
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aNeurobiología _0comprobar BNE19900967574 _2embne _9139039
650		7	_aNeurociencias _0comprobar BNE20012490612 _2embne _9158907
700	1		_aPandey, Girdhar K. _985242 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-07827-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319078274
907			_a.b12818926 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b20-06-17 _cm _dz _eu _feng _ggw _h4
945			_aQP356.2 .P36 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11548149 _z06-04-17
999			_c76274 _d76274 _x1