000			03739nam a22004095i 4500
001			76265
003			ES-MaUEC
005			20230207040216.0
007			cr nn 008mamaa
008			140902s2014 gw s 000 0 eng d
020			_a9783319073958
024	7		_a10.1007/978-3-319-07395-8 _2doi
040			_aES-MaUEC
050		4	_aQR185.8.T2 _bT73 2014 EB
082	0	4	_a616.079
245	0	0	_aTranscriptional Control of Lineage Differentiation in Immune Cells _cedited by Wilfried Ellmeier, Ichiro Taniuchi
260			_aCham, Switzerland _bSpringer International Publishing _c2014
300			_a1 recurso en línea (VIII, 331 p.) :
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v381
505	0		_aGenetic and epigenetic control of early lymphocyte development -- The role of BTB-zinc finger transcription factors during T cell development and in the regulation of T cell-mediated immunity -- Transcriptional control of the development and function of Vα14i NKT cells -- Transcriptional Control of Regulatory T cells -- Transcriptional regulatory networks for CD4 T cell differentiation -- Transcriptional control of NK cell differentiation and function -- Transcriptional control of pre-B cell development and leukemia prevention -- Transcription factors controlling innate lymphoid cell fate decisions -- Transcriptional control of dendritic cell differentiation -- Helper T cell plasticity: Impact of Extrinsic and Intrinsic Signals On Transcriptomes and Epigenomes
520			_aInsights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during Th differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity, and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aLinfocitos T _0comprobar BNE19912601605 _2embne _9144344
650		7	_aLinfocitos _9140675 _0comprobar BNE19900988218 _2embne
650		7	_aInmunología _0comprobar BNE19900958507 _2embne _9138330
700	1		_aEllmeier, Wilfried _eeditor literario _0Local _985229
700	1		_aTaniuchi, Ichiro _eeditor literario _985230 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-07395-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319073958
907			_a.b12818835 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b19-06-17 _cm _dz _eu _feng _ggw _h0
945			_aQR185.8 .T2 T73 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11548058 _z06-04-17
999			_c76265 _d76265 _x1