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007			cr nn 008mamaa
008			130930s2014 gw | s |||| 0|eng d
020			_a9783319013367
024	7		_a10.1007/978-3-319-01336-7 _2doi
040			_aES-MaUEC
050		4	_aQH324.2 _b.K66 2014 EB
082	0	4	_a610
100	1		_aKonieczny, Leszek _985157 _0Local
245	1	0	_aSystems biology : _bfunctional strategies of living organisms _cby Leszek Konieczny, Irena Roterman-Konieczna, Pawel Spólnik
260			_aCham _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XIII, 204 p.) _b157 ilustraciones, 91 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_a1.-The Structure and Function of Living Organisms -- General physiochemical properties of biological structures -- Self-organization -- Hypothesis - Protein folding simulation hypothesis - late stage intermediate -role of water --2.- Energy in Biology -Demand and Use -- General principles of thermodynamics -- Biological energy sources -Synthesis of water -- ATP synthesis -- Photosynthesis -- Direct and indirect exploitation of energy sources -- Energy conversion efficiency in biological processes -- Entropic effects -- Energy requirements of organisms --3.- Information as a Role and Meaning in Organisms -- Information as a quantitative concept. - Reliability of information sources -- Types of information conveyed by DNA -- Information entropy and mechanisms assisting selection -- The role of information in interpreting pathological events -- Hypothesis - Protein folding early stage intermediate -- 4.-Regulation in Biological Systems -- The cell and the organism -- The principle and mechanism of automatic intracellular regulation -- Regulatory coupling between cells and organisms -Hierarchical properties of regulation -- Regulatory mechanisms on the organism level -- Basic principles of regulation in biology -- Regulation levels -- Hypothesis - Proteome construction hypothesis -- 5.-Interrelationships in Organized Biological Systems -- The need of mutual relations in biological systems -- Cooperation and coordination -- The characteristics of process coordination in individual cells and organisms -- Mutual relationship between cells and the organism -Activation and inhibition of enzymes (rapid effects) -- Mutual support between cells and the organism -Interdependence related to gene expression (slow effects) -- Specialization of cell interrelationships -- Hypothesis - The criteria of life -- References -- Index
520			_aThe objective of this book is to present the strategies employed by living organisms on a molecular level and to help understand the basics of Systems Biology. Its content is organized in a way to meet the exponential growth in the volume of biological knowledge, and the need for a multidisciplinary approach in the practice of teaching modern biology. For this reason, the whole material is divided into five chapters, each devoted to a fundamental concept: Structure-Function, Energy, Information, Regulation and Interrelationships. The book describes generic mechanisms which occur in biology and promotes a simulation-based approach to the subject of Systems Biology. The use of basic knowledge as the background for presenting biological problems obligates the teachers to deal with generalized phenomena comprising the ever increasing volume of teaching materials. This book is intendedfor biologists and is informative forspecialists in the areas of computer science, robotics and engineering
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aBioinformática _0comprobar BNE20022028248 _2embne _9160489
650	0	7	_aSistemas biológicos _2embne _9403517
650		7	_aCitología _0comprobar BNE19900972907 _2embne _9139477
700	1		_aRoterman-Konieczna, Irena _985158 _0Local
700	1		_aSpólnik, Pawel _985159 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-01336-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319013367
907			_a.b1281832x _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b19-05-17 _cm _dz _eb _feng _ggw _h0
945			_aQH324.2 .K66 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11547546 _z06-04-17
999			_c76214 _d76214 _x1