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001			76210
003			ES-MaUEC
005			20230207040214.0
007			cr nn 008mamaa
008			130924s2014 gw | s |||| 0|eng d
020			_a9783319010083
024	7		_a10.1007/978-3-319-01008-3 _2doi
040			_aES-MaUEC
050		4	_aRC662.4 _b.S97 2014 EB
082	0	4	_a610
245	0	2	_aA Systems biology approach to study metabolic syndrome _cedited by Matej Oresic, Antonio Vidal-Puig
260			_aCham _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XIX, 384 p.) _b47 ilustraciones, 23 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aThe metabolic syndrome and its complex pathophysiology -- Systems biology in human health and disease -- The liver in metabolic syndrome -- Role of adipose tissue in the pathogenesis and treatment of metabolic syndrome -- The beta cell in metabolic syndrome -- The skeletal muscle in metabolic syndrome -- The central nervous system in metabolic syndrome -- Lipid metabolism in metabolic syndrome -- Gut microbiota in metabolic syndrome -- Proteomics in the systems-level study of the metabolic syndrome -- Metabolomics in the systems-level study of the metabolic syndrome -- Fluxomics -- In vitro colon model to study metabolic syndrome -- Genome-scale modeling of tissue and cancer metabolism -- Modeling of lipid membranes and lipoproteins -- Computational statistics approaches to study metabolic syndrome -- Towards modeling of metabolic syndrome: Tissue crosstalk in lipid spillover
520			_aThe aim of this book is to provide the target audience, specifically students of Medicine, Biology, Systems Biology and Bioinformatics, as well as experienced researchers in research fields relevant to metabolic syndrome (MetS) with an overview of the challenges and opportunities in systems biology and how it can be used to tackle MetS. In particular, the aims are: (1) to provide an introduction to the key biological processes involved in the pathophysiology of MetS; (2) through the use of specific examples, provide an introduction to the latest technologies that use a systems biology approach to study MetS; and (3) to give an overview of the mathematical modeling approaches for studying MetS. The clearly written chapters by leading experts in the field provide detailed descriptions crucial for the unique position of this book and its focus on the application of systems biology to tackle specific pathophysiologically relevant aspects of MetS and provide a valuable practical guide to this research community
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aSíndrome metabólico _0comprobar BNE20051345698 _2embne _9165022
650		7	_aEndocrinología _0comprobar BNE19900971669 _2embne _9139372
700	1		_aOresic, Matej _eeditor literario _985152 _0Local
700	1		_aVidal-Puig, Antonio _eeditor literario _985153 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-01008-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319010083
907			_a.b12818288 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b17-05-17 _cm _dz _eb _feng _ggw _h2
945			_aRC662.4 .S97 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11547509 _z06-04-17
999			_c76210 _d76210 _x1