| 000 | 02580nam a2200385 c 4500 | ||
|---|---|---|---|
| 001 | 76203 | ||
| 003 | ES-MaUEC | ||
| 005 | 20230202101940.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 130518s2013 gw | s |||| 0|eng d | ||
| 020 | _a9783319003030 | ||
| 024 | 7 |
_a10.1007/978-3-319-00303-0 _2doi |
|
| 040 | _aES-MaUEC | ||
| 050 | 4 |
_aQR82.M8 _bI76 2013 EB |
|
| 082 | 0 | 4 | _a579 |
| 245 | 0 | 0 |
_aIron acquisition by the genus mycobacterium : _bhistory, mechanisms, role of siderocalin, anti-tuberculosis drug development _cedited by B. Rowe Byers |
| 260 |
_aHeidelberg _bSpringer International Publishing _c2013 |
||
| 300 |
_a1 recurso en línea (V, 92 p.) _b39 ilustraciones, 9 ilustraciones en color |
||
| 336 |
_aTexto (visual) _btxt _2rdacontent |
||
| 337 |
_aelectrónico _bc _2rdamedia |
||
| 338 |
_arecurso electrónico _bcr _2rdacarrier |
||
| 490 | 1 |
_aSpringerBriefs in Molecular Science _x2191-5407 |
|
| 505 | 0 | _aA History of Iron Metabolism in the Mycobacteria -- Mycobacterial Iron Uptake Mechanisms -- Siderocalin Combats Mycobacterial Infections -- Design of Anti-TB Drugs Using the Iron Uptake Platform | |
| 520 | _aIron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described. The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed. The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs and/or conjugates | ||
| 942 |
_2lcc _cLE |
||
| 988 | _aEBOOK, EBSPRINGERrevisando | ||
| 650 | 7 |
_aMicobacterias _9146809 _0comprobar BNE19925032000 _2embne |
|
| 650 | 7 |
_aMicrobiología _0comprobar BNE19900962962 _2embne _9138684 |
|
| 700 | 1 |
_aByers, B. Rowe _eeditor literario _985143 _0Local |
|
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-00303-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 901 | _ai9783319003030 | ||
| 907 |
_a.b12818215 _b10-10-17 _c01-10-14 |
||
| 998 |
_am _a_alco _a_vill _b17-05-17 _cm _dz _eb _feng _ggw _h0 |
||
| 945 |
_aQR82 .M8 I76 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11547431 _z06-04-17 |
||
| 999 |
_c76203 _d76203 _x1 |
||