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001			76194
003			ES-MaUEC
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007			cr nn 008mamaa
008			130628s2013 sz | s |||| 0|eng d
020			_a9783034806794
024	7		_a10.1007/978-3-0348-0679-4 _2doi
040			_aES-MaUEC
050		4	_aQP623 _b.B37 2013 EB
082	0	4	_a591.35
100	1		_aBarrett, Lucy W. _985127 _0Local
245	1	0	_aUntranslated gene regions and other non-coding elements : _bregulation of eukaryotic gene expression _cby Lucy W. Barrett, Sue Fletcher, Steve D. Wilton
260			_aBasel _bSpringer International Publishing _c2013
300			_a1 recurso en línea (VIII, 56 p.) _b2 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aSpringerBriefs in Biochemistry and Molecular Biology _x2211-9353
505	0		_aIntroduction -- Promoter -- 5 Untranslated Region -- Structure -- Intronic Regions -- 3 Untranslated Region -- Non-coding RNAs -- Conclusion
520			_aThere is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as junk DNA, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5 and 3 untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aARN _0comprobar BNE19913480892 _2embne _9144940
650		7	_aGenética humana _0comprobar BNE19900986777 _2embne _9140562
700	1		_aFletcher, Sue _0Local _985128
700	1		_aWilton, Steve D. _985129 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-0348-0679-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783034806794
907			_a.b12818124 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b19-05-17 _cm _dz _eb _feng _gsz _h0
945			_aQP623 .B37 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11547340 _z06-04-17
999			_c76194 _d76194 _x1