000			02899nam a22004215i 4500
001			76193
003			ES-MaUEC
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007			cr nn 008mamaa
008			130723s2013 sz | s |||| 0|eng d
020			_a9783034806640
024	7		_a10.1007/978-3-0348-0664-0 _2doi
040			_aES-MaUEC
050		4	_aRC271.T36 _bM39 2013 EB
082	0	4	_a614.5999
100	1		_aMaximov, Philipp Y. _985124 _0Local
245	1	0	_aTamoxifen : _bpioneering medicine in breast cancer _cby Philipp Y. Maximov, Russell E. McDaniel, V. Craig Jordan
260			_aBasel _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XXII, 199 p.) _b54 ilustraciones, 32 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aMilestones in Drug Therapy
505	0		_aDiscovery and Pharmacology of Nonsteroidal Estrogens and Antiestrogens -- Tamoxifen Goes Forward Alone -- Metabolites of Tamoxifen as the Basis of Drug Development -- Adjuvant Therapy $17F (B The Breakthrough -- The Wisconsin Story in the 1980$17F (Bs: Discovery of Target Site Specific Estrogen Action -- Carcinogenesis and Tamoxifen -- Chemoprevention: Cinderella waiting for the ball -- Tamoxifen and Raloxifene head to head: The STAR TRIAL -- Acquired resistance to Tamoxifen: back to the beginning -- The legacy of Tamoxifen -- Appendix: Four decades of discovery in breast cancer research and treatment $17F (B an interview with V. Craig Jordan by Marc Poirot -- Selected Awards that Recognize the Contribution of Tamoxifen and Raloxifene to Medicine
520			_aTamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the $1! @(Bfather of tamoxifen$1(N((B£ð~`éP¡?éÅ
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aTamoxifeno _9144989 _0comprobar BNE19913483402 _2embne
650	0	7	_aCáncer _xInvestigación _0LocalV _2embne _9182523
650	0	7	_aOncología _0LocalV _2embne _9139207
700	1		_aMcDaniel, Russell E. _985125 _0Local
700	1		_aJordan, V. Craig _0Local _985126
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-0348-0664-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783034806640
907			_a.b12818112 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b16-05-17 _cm _dz _eb _feng _gsz _h0
945			_aRC271 .T36 M39 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11547339 _z06-04-17
999			_c76193 _d76193 _x1