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007			cr nn 008mamaa
008			140527s2014 fr | s |||| 0|eng d
020			_a9782817804668
024	7		_a10.1007/978-2-8178-0466-8 _2doi
040			_aES-MaUEC
050		4	_aQP106.6 _b.M65 2014 EB
082	0	4	_a611.01816
245	0	0	_aMolecular mechanisms of angiogenesis : _bfrom ontogenesis to oncogenesis _cedited by Jean-Jacques Feige, Gilles Pagès, Fabrice Soncin
260			_aParis _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XI, 505 p.) _b64 ilustraciones, 58 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aEmergence of Endothelial Cells During Vascular Development -- Lymphatic Vascular Morphogenesis -- Finding New Partnerships; The Function of Individual Extracellular Receptor Domains in Angiogenic Signalling by VEGF Receptors -- Wnt/ Frizzled Signaling in the Vasculature -- BMP9, BMP10 And ALK1: An Emerging Vascular Signaling Pathway With Therapeutic Applications -- Apeling Signaling in Retinal Angiogenesis -- Emerging Role of the Two Related Basic Helix-Loop-Helix Proteins -- TAL1 and LYL1 In Angiogenesis -- Hypoxia and Extracellular Matrix Remodeling -- Sphingosine-1-Phosphate in Hypoxic Signaling -- Reciprocal Crosstalk Between Angiogenesis and Metabolism -- Endothelial Progenitor Cells and Cardiovascular Ischemic Diseases: Characterization, Functions and Potential Clinical Applications as Biomarker and Therapeutic Tools -- Endothelial Cell Reactions to Oxygen: Implications For Cancer -- Tumor Angiogenesis and Lymphangiogenesis: Microenvironmental Soil For Tumor Progression And Metastatic Dissemination -- Angiogenesis And Invasion in Malignant Glioma: Friends or Foes? -- Role of Endothelial Cells in Tumor Escape From Immunity -- Tumor High-Endothelial Venules and Lymphocyte Trafficking -- Post-Transcriptional Regulation of Angiogenesis Through AU-Rich Mrna Degradation: Potential Application in Cancer Therapy -- Antiangiogenic Drugs in Cancer Therapy, Effect on Advanced Renal Cell Carcinoma -- Anti-Angiogenic Therapies in Colorectal Cancer -- Resistance to Anti-Angiogenic Treatments via Up-Regulation of Substitution Pathways -- VEGF-A Splice Variants: Do They Play a Role in Tumor Responses to Anti-Angiogenic Therapies? -- Progenitor Endothelial Cells as Biomarkers of Anti-Vascular Agents -- Soluble Vascular Endothelial (VE)-Cadherin : Toward a Marker of Endotelial Dysfunction -- The Prognostic and Predictive Value of VEGF Across Various Tumor Types
520			_aAngiogenesis is a multi-stage process that drives the generation of new blood and lymphatic vessels from pre-existing ones. It is highly active during embryogenesis, largely inactive during adulthood but reactivated during wound healing and under a number of pathological conditions including cancer and ocular diseases. In addition to endothelial cells, which line the walls of the vessels, several other cell types (pericytes, macrophages, progenitor cells) also contribute to angiogenesis. A number of signaling pathways are activated and very finely tune the delicate morphogenetic events that ultimately lead to the formation of stable bloodproof neovessels. This book reviews recent advances in our understanding of the molecular and cellular mechanisms of angiogenesis, with a focus on how to integrate these observations into the context of developmental, post-natal and pathological neovascularization. The book was published under the auspices of the French Angiogenesis Society. Most contributors are prominent members of this Society or international researchers who have actively contributed to the Annual Meetings of the Society
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aNeovascularización _0comprobar BNE20050602435 _2embne _9164656
650		7	_aCáncer _xInvestigación _0comprobar BNE19901364217 _2embne _9182523
650		7	_aMedicina nuclear _0comprobar BNE19900959317 _2embne _9138396
700	1		_aFeige, Jean-Jacques _eeditor literario _985113 _0Local
700	1		_aPagès, Gilles _eeditor literario _985114 _0Local
700	1		_aSoncin, Fabrice _eeditor literario _985115 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-2-8178-0466-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9782817804668
907			_a.b12818057 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b16-05-17 _cm _dz _eb _feng _gfr _h0
945			_aQP106.6 .M65 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11547273 _z06-04-17
999			_c76187 _d76187 _x1