000			04058nam a22003855i 4500
001			76172
003			ES-MaUEC
005			20230207040212.0
007			cr nn 008mamaa
008			100301s2006 xxu s 001 0 eng d
020			_a9781597450584
024	7		_a10.1007/978-1-59745-058-4 _2doi
040			_aES-MaUEC
050		4	_aRC455.4.A54 _bT73 2006 EB
082	0	4	_a612.8
245	0	0	_aTransgenic and Knockout Models of Neuropsychiatric Disorders _cedited by Gene S. Fisch, Jonathan Flint
264		1	_aTotowa, NJ _bHumana Press _c2006
300			_a1 recurso en línea (296 páginas)
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aContemporary Clinical Neuroscience
505	0		_aand Overview -- Transgenic and Knockout Models of Psychiatric Disorders -- Transgenic Mouse Models and Human Psychiatric Disease -- Transgenic and Knockout Mouse Models -- If Only They Could Talk -- Transgenic and Knockout Models of Neurocognitive Dysfunction -- Spinocerebellar Ataxia Type 1 -- Mouse Models of Hereditary Mental Retardation -- How Can Studies of Animals Help to Uncover the Roles of Genes Implicated in Human Speech and Language Disorders? -- Animal Models of Autism -- Transgenic and Knockout Models of Neuropsychiatric Dysfunction -- Genetic Mouse Models of Psychiatric Disorders -- Animal Models of Psychosis -- Animal Models of Anxiety -- Modeling Human Anxiety and Depression in Mutant Mice -- Mutant Mouse Models of Bipolar Disorder.
520	3		_aNeuroscientists are now establishing meaningful genotype-phenotype relationships for complex neurobehavioral and neuropsychiatric disorders and even creating animal models for these dysfunctions. These developments have made it imperative to know when such transgenic and knockout models are valid for the human disorders they represent. In Transgenic and Knockout Models of Neuropsychiatric Disorders, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, as well as speech disorders, and disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder. Timely introductory articles debate the alleged continuity of species of human and infrahuman behavior (Darwin), the utility of infrahuman animals in understanding human behavior and psychiatric disease, and the suitability of nonhuman models of complex neuropsychiatric dysfunctions involving language. Comprehensive and systematic, Transgenic and Knockout Models of Neuropsychiatric Disorders offers a clear assessment of whether genetic abnormalities produced from infrahuman models manifest the neuropsychiatric disorders to which they correspond in humans and how best they may be used to carry out successful research today.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aEnfermedades mentales _0comprobar BNE19900967620 _2embne _9139043
650		7	_aEnfermedades mentales _xAspectos genéticos _9291096 _0comprobar BNE20000550437 _2embne
700	1		_aFisch, Gene S. _0n 2002021788 _eeditor literario _948618
700	1		_aFlint, Jonathan _0n 2005183026 _eeditor literario _948619
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-59745-058-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12817909 _b14-11-17 _c01-10-14
998			_am _a_alco _a_vill _b14-11-17 _cm _dz _ea _feng _gxxu _h0
945			_aRC455.4.A54 T73 2006 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11547121 _z06-04-17
999			_c76172 _d76172 _x1