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008			140823s2014 xxu| s |||| 0|eng d
020			_a9781493911547
024	7		_a10.1007/978-1-4939-1154-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP702.G577 _bY876 2014
082	0	4	_a612.8
100	1		_aYu, Robert K. _eeditor literario _985059 _0Local
245	1	0	_aGlycobiology of the Nervous System _cedited by Robert K. Yu, Cara-Lynne Schengrund.
260			_aNew York _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XVII, 584 p.) _b123 ilustraciones, 59 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aAdvances in Neurobiology _x2190-5215 _v9
505	0		_aIntroduction to the Complexity of Cell Surface and Tissue Matrix Glycoconjugates -- Introduction to Cells Comprising the Nervous System -- Synthesis, Processing, and Function of N-glycans in N-glycoproteins -- Synthesis of O-linked Glycoconjugates in the Nervous System -- Chemistry and Function of Glycosaminoglycans in the Nervous System -- Use of Glycan-targeted Antibodies/Lectins to Study the Expression/Function of Glycosyltransferases in the Nervous System -- From Mass Spectrometry-based Glycosylation Analysis to Glycomics and Glycoproteomic -- Structural Analysis of Oligosaccharides and Glycoconjugates using NMR -- Glycolipid and Glycoprotein Expression During Neural Development -- Gangliosides and Cell Surface Ganglioside Glycohydrolases in the Nervous System -- Role of Myelin-Associated Glycoprotein (Siglec-4a) in the Nervous System -- Role of Galactosylceramide and Sulfatide in Oligodendrocytes and CNS Myelin: Formation of a Glycosynapse -- Glycosignaling â€{u0060}General Review -- Glycosphingolipids in the Regulation of the Nervous System -- Glycobiology of Ion Transport in the Nervous System -- O-GlcNAcylation of Neuronal Proteins: Roles in Neuronal Functions and in Neurodegeneration -- N-glycosylation in Regulation of the Nervous System -- Roles of Carbohydrates in the Interaction of Pathogens with Neural Cells -- Glycoconjugate Changes in Aging and Age-related Diseases -- Gangliosides and Glycolipids in Neurodegenerative Disorders -- Glycosidases: Inborn Errors of Glycosphingolipid Catabolism -- Ganglioside Storage Diseases: On the Road to Management -- Dynamic Aspects of Neural Tumor Gangliosides -- Galectins and Neuroinflammation -- Glycoconjugates and Neuroimmunological Diseases.
520			_aA thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.
650		0	_9146728 _aNeuroquímica
650		7	_aNeurobiología _2embne _9139039
700	1		_aSchengrund, Cara-Lynne _eeditor literario _985060 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-1154-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12817715 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQP702.G577 Y876 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11546931 _z06-04-17
988			_aEBOOK, EBSPRINGERrevisando
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0