000			03987nam a22003855i 4500
999			_c76146 _d76146 _x1
001			76146
003			ES-MaUEC
005			20230207040211.0
007			cr nn 008mamaa
008			140728s2014 xxu| s |||| 0|eng d
020			_a9781493910564
024	7		_a10.1007/978-1-4939-1056-4 _2doi
040			_bspa _dES-MaUEC
050		4	_aQP376 _b.P676 2014
082	0	4	_a612.8
100	1		_aPopoli, Maurizio. _eeditor. _985047 _0Local
245	1	0	_aSynaptic Stress and Pathogenesis of Neuropsychiatric Disorders _cedited by Maurizio Popoli, David Diamond, Gerard Sanacora.
260			_aNew York _bSpringer _c2014
300			_a1 recurso en línea (XIV, 355 p.) _b49 ilustraciones, 48 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aÂ{u4A25} Brain on Stress: The Good and the Bad -- Regulation of Excitatory Synapses by Stress Hormones -- Synaptic Stress, Changes in Glutamate Transmission and Circuitry, and Psychopatology -- Dual Regulation of Glutamatergic Transmission and Cognition by Stress in Prefrontal Cortex -- Role of Endocannabinoids in Regulating Glucocorticoid Effects on Memory for Emotionally Arousing Experiences -- Endocannabinoid Signaling & Synaptic Plasticity During Stress -- Stress Induced Metaplasticity at GABA Synapses -- Stress Modulation of Synaptic Plasticity in the Hippocampus -- Neural-Cognitive Effects of Stress in the Hippocampus -- Evolutionary, Historical and Mechanistic Perspectives on How Stress Affects Memory and Hippocampal Synaptic Plasticity -- Acute Stress Disrupts Short- and Long-term Patterns of Synaptic Plasticity in Dorsal Hippocampus and Subiculum: Implications for Hippocampal Output and Behaviour -- Synaptic Mechanisms and Cognitive Computations Underlying Stress Effects on Cognitive Function -- Altered GABA Function in Major Depression -- Pathology in Astroglia, Glutamate and GABA in Major Depressive Disorder: Evidence from Studies of Human Postmortem Tissue -- Evidence of Glutamatergic Dysfunction in the Pathophysiology of Schizophrenia -- Metabolic Stress and Neuropsychiatric Disorders -- Using our Understanding of Stress Related Effects on Glutamate Neurotransmission to Guide the Development of Novel Treatment Strategies.
520			_aAn overview of the ways in which stress affects brain function or synaptic plasticity and can precipitate the onset of neuropsychiatric disorders. Recent research has shown that changes in glutamate/GABA synapses and related pathways are involved in determining whether the effects of a particular stressor will be adaptive or maladaptive. Among the topics discussed are the impact of behavioral stress and glucocorticoids on tripartite glutamate synapses and synaptic transmission, the way that psychiatric drugs affect these same mechanisms, and how the molecular/cellular/functional effects of stress may trigger disorders such as depression, schizophrenia, anxiety, and PTSD. The results presented have been obtained through a range of different and complementary methods including live imaging, electrophysiology, glutamate release from isolated live synaptic terminals, transgenic and animal models, and new behavioral methods.
650		7	_2embne _aCerebro _9139532
700	1		_aDiamond, David _eeditor literario _985048 _0Local
700	1		_aSanacora, Gerard _eeditor literario _985049 _0Local
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-1056-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12817648 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQP376 .P676 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11546864 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0