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008			140926s2014 xxu| s |||| 0|eng d
020			_a9781493909742
024	7		_a10.1007/978-1-4939-0974-2 _2doi
040			_bspa _dES-MaUEC
050		4	_aQP363.2 _bP377 2014
082	0	4	_a612.8
100	1		_aParpura, Vladimir. _eeditor. _985037 _0Local
245	1	0	_aPathological Potential of Neuroglia : _bPossible New Targets for Medical Intervention _cedited by Vladimir Parpura, Alexei Verkhratsky.
260			_aNew York _bSpringer _c2014
300			_a1 recurso en línea (XVI, 541 p.) _b74 ilustraciones, 48 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aGeneral Pathophysiology of Neuroglia: Neurological and Psychiatric Disorders as Gliopathies -- Ionic Signaling in Physiology and Pathophysiology of Astroglia -- Pathophysiology of Vesicle Dynamics in Astrocytes -- Glial Glutamate and Metabolic Transporters as a Target for Neurodegenerative Therapy and Biomarkers -- Alexander Disease and Astrotherapeutics -- Role of Astrocytes in Central Nervous System Traum -- Astroglial and Neuronal Integrity During Cortical Spreading Depolarization -- Crucial role for astrocytes in epilepsy -- Microglial Biology in Neuoinflammatory Disease: Phamaco-industrial Approach to Target Validation -- The Role of Astrocytes in Huntington's Disease -- Amyotrophic Lateral Sclerosis: A Glial Perspective -- Complex and Associated Astroglial and Microglial Changes during the Progression of AlzheimerÂś Disease -- Possible Therapeutic Targets in Microglia -- Novel Therapeutic Approaches to Malignant Gliomas -- Hepatic encephalopathy: A Primary Neurogliopathy -- Astroglia and Severe Mental Illness: A Role for Glutamate Microdomains -- Emerging Roles for Glial Pathology in Addiction -- Astroglial Connexins as Elements of Sleep-wake Cycle Regulation and Dysfunction -- Experimental Treatment of Acquired and Inherited Neuropathies -- Satellite glial cells as target for chronic pain therapy -- Enteric Glial Cells: Implications in Gut Pathology.
520			_aPathophysiological states, neurological and psychiatric diseases are almost universally considered from the neurocentric point of view, with neurons being the principal cellular element of pathological process. The brain homeostasis, which lies at the fulcrum of healthy brain function, the compromise of which invariably results in dysfunction/disease, however, is entirely controlled by neuroglia. It is becoming clear that neuroglial cells are involved in various aspects of initiation, progression and resolution of neuropathology.Â{u026E} this book we aim to integrate the body of information that has accumulated in recent years revealing the active role of glia in such pathophysiological processes.Â{u056E}derstanding roles of glial cells in pathology will provide new targets for medical intervention and aide the development of much needed therapeutics. This book will be particularly useful for researchers, students, physicians and psychotherapists working in the field of neurobiology, neurology and psychiatry.
650		7	_2embne _9163919 _aNeuroglia
700	1		_aVerkhratsky, Alexei _eeditor literario _985038 _0Local
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-0974-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12817594 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQP363.2 P377 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11546815 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0