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008			140709s2014 xxu| s |||| 0|eng d
020			_a9781493908592
024	7		_a10.1007/978-1-4939-0859-2 _2doi
050		4	_aRC268.48 _b.C36 2014 EB
082	0	4	_a616.079
245	0	0	_aCancers in People with HIV and AIDS : _bProgress and Challenges _cedited by Robert Yarchoan
260			_aNew York _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XVI, 389 p.) _b34 ilustraciones, 20 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aHIV-associated Cancers: Overview -- Epidemiology of AIDS-defining Malignancies -- Epidemiology of non-AIDS Defining Malignancies -- HIV Cancers in Resource-limited Regions -- Kaposi's Sarcoma-associated Herpesvirus (KSHV) -- Epstein Barr Virus (EBV) -- Human Papillomavirus (HPV) -- Merkel Cell Polymavirus (MCV) -- Presentation and Pathogenesis of Kaposi's Sarcoma -- Management of Kaposi's Sarcoma -- Presentation and Pathogenesis of HIV Lymphomas -- Diffuse Large B-Cell Lymphoma -- Burkitt and Burkitt-Like Lymphoma -- Primary Effusion Lymphoma -- AIDS-related Central Nervous System Lymphoma -- Plasmablastic and Other Lymphomas -- Hodkin Lymphoma -- Multicentric Castelman Disease -- Cervical Cancer -- Anal Cancer -- Other HPV-Associated Cancers -- Lung Cancer in HIV Infection -- Hepattocellular Carcinoma in HIV-positive Patients -- Merkel Cell Carcinoma and Other HIV-associated Skin Cancers -- Conjuctival Carcinoma -- Malignancies in Children with HIV Infection -- cART and Supportive Care -- Stem Cell Transplantation
520	3		_aThe association between AIDS and cancer was recognized from the beginning of the AIDS epidemic, when the appearance of Kaposi sarcoma in a cluster of young men was one of the first signs of this new disease. It was soon recognized that AIDS was caused by infection with a novel virus (HIV) and that AIDS patients are prone to develop a number of 2AIDS-defining3 cancers: Kaposi sarcoma, lymphoma, and cervical cancer. The development of effective combination anti-HIV therapy starting around 1996 converted AIDS from a death sentence to a manageable disease and led to dramatic shifts in the epidemic. As this therapy was able to improve immune function in patients, the incidence of most 2AIDS-defining3 cancers decreased. There is a misconception, however, that AIDS has gone away. In fact, as AIDS patients are living longer, the number of AIDS patients has more than doubled in the United States since 1996, and the AIDS population overall has increased in age. Also, as AIDS patients are less likely to die of other complications, cancer is coming to the forefront as one of the most common causes of death in regions where AIDS drugs are widely available. Moreover, the three 2AIDS-defining3 cancers are now taking a back seat to a number of other HIV-associated cancers, such as Hodgkin lymphoma, lung cancer, and anal cancer. In the developing world, AIDS-associated cancers are a major public health problem, and in some regions of sub-Saharan Africa, Kaposi sarcoma is the most common tumor in men. In recent years, there has been a vast increase in our understanding of HIV-associated cancers. We now know, for example, that most are caused by other viruses and that the main role of HIV and immunodeficiency is to provide a supportive environment for the viruses to multiply and for the cancers to develop. But there remain a number of unanswered questions and a need for improved prevention and therapy. In the 28 chapters of this book, written by some of the most renowned experts in this field, we present up-to-date information on the cancers associated with HIV infection. The chapters cover the epidemiology of these cancers, their pathogenesis, their clinical presentation, and their treatment. The book will be of value to physicians, other medical professionals, students, and researchers with an interest in AIDS, viral-associated cancers, or HIV-associated malignancies
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aCáncer _xEtiología _9170296 _0comprobar BNE19901092798 _2embne
700	1		_aYarchoan, Robert _eeditor literario _985029 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-0859-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781493908592
907			_a.b12817545 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b11-08-17 _cm _dz _ek _feng _gxxu _h0
945			_aRC268.48 .C36 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11546761 _z06-04-17
999			_c76136 _d76136 _x1