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008			140515s2014 xxu| s |||| 0|eng d
020			_a9781493908233
024	7		_a10.1007/978-1-4939-0823-3 _2doi
040			_bspa _dES-MaUEC
050		4	_aQP572.G45 _bP678 2014
082	0	4	_a612.8
100	1		_aPortelli, Jeanelle. _eeditor. _985026 _0Local
245	1	0	_aCentral Functions of the Ghrelin Receptor _cedited by Jeanelle Portelli, Ilse Smolders.
260			_aNew York _bSpringer _c2014
300			_a1 recurso en línea (XVII, 214 p.) _b12 ilustraciones, 7 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aThe Receptors _v25
505	0		_aConstitutive activity of the ghrelin receptor -- Homodimerization and heterodimerization of the ghrelin receptor -- The role of the ghrelin receptor in appetite and energy metabolism -- The vagus nerve and ghrelin function -- Central Ghrelin Receptors and Food Intake -- Ghrelin receptors a novel target for obesity -- Ghrelin receptor antagonism as a potential therapeutic target for alcohol use disorders: a preclinical perspective -- Clinical Research on the Ghrelin Axis and Alcohol Consumption -- Ghrelin and Sleep Regulation -- Ghrelin and Memory -- Ghrelin receptors and Epilepsy -- Ghrelin plays a role in various physiological and pathophysiological brain functions -- Ghrelin and Parkinsonâ€{u3804}isease.
520			_aThe Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been shown to affect various processes, such as food intake, gut motility, memory, glucose and lipid metabolism, cardiovascular performances, reproduction, memory, and immunological responses, amongst others. The functions of the ghrelin receptor in the central nervous system are numerous and are still being explored. In this book we specifically focus on the various roles of the ghrelin receptor in the central nervous system. In a first set of chapters, the book will focus on the discovery and the properties of this intriguing constitutively active G-protein coupled receptor, on its multiple intracellular transduction mechanisms and the various subtypes of the currently known ghrelin receptor complexes. Next, the book will elaborate on the mitochondrial mechanisms regulated by the ghrelin receptor, its role in feeding and drug addictive mechanisms, memory, sleep and arousal. The final chapters focus on the potential of this receptor as a target for the treatment of neurological disorders including Parkinsonâ€{u3824}isease, epilepsy, anxiety and depression.
650		7	_2embne _9138583 _aHormonas
650		7	_9676519 _aSustancias orgánicas naturales
700	1		_aSmolders, Ilse _eeditor literario _985027 _0Local
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-0823-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12817521 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQP572.G45 P678 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11546748 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0