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008			140419s2014 xxu| s |||| 0|eng d
020			_a9781493907151
024	7		_a10.1007/978-1-4939-0715-1 _2doi
040			_dES-MaUEC
050		4	_aQH441 _b.E464 2014
082	0	4	_a570
100	1		_aEl-Metwally, Sara _0Local _985019
245	1	0	_aNext Generation Sequencing Technologies and Challenges in Sequence Assembly _cby Sara El-Metwally, Osama M. Ouda, Mohamed Helmy.
260			_aNew York _bSpringer _c2014
300			_a1 recurso en línea (XII, 118 p.) _b12 ilustraciones, 1 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aSpringerBriefs in Systems Biology _x2193-4746 _v7
505	0		_aBasics of Molecular Biology for Next-generation Sequencing -- Algorithms and Data Structures in Next-generation Sequencing -- First- and Next-generations Sequencing Models -- Next-generation Sequencing Platforms -- Challenges in Next-generation Sequencing Field -- New Horizons in Next-generation Sequencing -- Novel Next-generation Sequencing Applications -- Next-generation Sequence Assembly Overview -- Approaches and Challenges of Next-generation Sequence Assembly Stages -- Assessment of Next-generation Sequence Assembly -- Next-generation Sequence Assemblers -- Concluding Remarks.
520			_aThe introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.
650		7	_2embne _9140562 _aGenética humana
700	1		_aOuda, Osama M. _985020 _0Local
700	1		_aHelmy, Mohamed _0Local _985021
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-0715-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12817478 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQH441 .E464 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11546694 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0