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001			76119
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007			cr nn 008mamaa
008			140328s2014 xxu| s |||| 0|eng d
020			_a9781493905096
024	7		_a10.1007/978-1-4939-0509-6 _2doi
050		4	_aRC659 _b.P75 2014 EB
082	0	4	_a611.01816
082	0	4	_a599.935
245	0	0	_aPrimary aldosteronism : _bMolecular Genetics, Endocrinology, and Translational Medicine _cedited by Per Hellman
260			_aNew York _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XI, 233 p.) _b25 ilustraciones, 17 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aIntroduction -- Primary Aldosteronism: Molecular Mechanisms and Diagnosis -- Epidemiology and need for screening -- Low renin hypertension -- Molecular derangements in sporadic primary aldosteronism -- From genetic abnormalities to pathophysiological mechanisms -- Familial hyperaldosteronism type I -- Familial hyperaldosteronism type II -- Familial hyperaldosteronism type III -- The Aldosterone-Renin Ratio: Role and Problems -- Confirmatory testing for Primary Aldosteronism -- Radiological imaging of adrenocortical tumors -- Aldosterone and cardiovascular disease -- Quality of life aspects of primary aldosteronism -- Medical treatment of primary aldosteronism -- Surgical treatment of primary aldosteronism -- Index
520			_aPrimary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene - KCNJ5 - in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisando
650		7	_aGlándulas suprarrenales _xEnfermedades _0comprobar BNE19912632755 _2embne _9185569
650		7	_aEndocrinología _0comprobar BNE19900971669 _2embne _9139372
700	1		_aHellman, Per _eeditor literario _985004 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-0509-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12817375 _b31-10-17 _c01-10-14
998			_am _a_alco _a_vill _b31-10-17 _cm _dz _eb _feng _gxxu _h0
945			_aRC659 .P75 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11546591 _z06-04-17
999			_c76119 _d76119 _x1