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008 131204s2013 xxu| s 000 0 eng d
020 _a9781461492337
024 7 _a10.1007/978-1-4614-9233-7
_2doi
040 _beng
050 4 _aQP551
_b.P75 2013 EB
082 0 4 _a572
245 0 0 _aProteases in Health and Disease
_cedited by Sajal Chakraborti, Naranjan S. Dhalla
260 _aNew York
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (XV, 403 p.)
_b84 ilustraciones, 37 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aAdvances in Biochemistry in Health and Disease
_v7
505 0 _aPart A: Molecular and Biochemical Aspects of Proteases -- 1. An Overview of Endoplasmic Reticulum Calpain System -- 2. Mitochondrial Calpains: Who, What, Where, When and Why? -- 3. Role of Calpains in Calmodulin Regulated Systems -- 4. Exercise and Matrix Metalloproteases: A Brief Overview -- 5. Regulation of Chondrocyte Matrix Metalloproteinase Gene Expression -- 6. Microbial Source of Fibrinolytic Protease and Its Biotechnological Potential -- 7. Aspartic Proteolytic Inhibitors Induce Cellular and Biochemical Alterations in Fungal Cells -- 8. Cysteine Proteases of Human Malaria Parasites -- 9. Proteases as Virulence Factors in Leishmania: Focus on Serine Proteases as Possible Therapeutic Targets -- 10. An Updated Inventory on Properties, Pathophysiology and Therapeutic Potential of Snake Venom Thrombin-like Proteases -- 11. Macrocyclic Protease Inhibitors Constrained into a β-Strand Geometry -- Part B: Involvement of Proteases in Disease Processes -- 12. Regulation of MT1-MMP Activation and Its Relevance to Disease Processes -- 13. Role of Proteases During Intra-erythrocytic Developmental Cycle of Human Malaria Parasite Plasmodium falciparum -- 14. Proteases in Vibrio cholerae and Their Role in Pathogenesis -- 15. ADAMTS13: The von Willebrand Factor Cleaving Protease and Its Role in Thrombotic Thrombocytopenic Purpura -- 16. Role of Proteases and Their Tissue Inhibitors in Pregnancy Outcome -- 17. Matrix Metalloproteinases in Bone Health and Disease -- 18. Escalated Expression of Matrix Metalloproteinases in Osteoarthritis -- 19. Role of Proteases in Autism Spectrum Disorder -- 20. Role of Proteases in the Management of Hepatitis C Virus -- 21. Role of Protease in Inflammatory Lung Diseases -- 22. Involvement of Some Proteolytic Enzymes in Cardiac Dysfunction Due to Ischemia-Reperfusion Injury.
520 _aIn view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases
650 7 _aProteínas
_xAnálisis
_9242917
_0comprobar BNE19971816444
_2embne
650 0 7 _aEnzimas proteolíticas
_9146220
_2embne
700 1 _aChakraborti, Sajal.
_eeditor literario
_984935
_0Local
700 1 _aDhalla, Naranjan S.
_eeditor literario
_0Local
_984616
830 0 _aAdvances in Biochemistry in Health and Disease
_v7
_9133167
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-9233-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b1281703x
_b10-10-17
_c01-10-14
942 _2lcc
_cLE
945 _aQP551 .P75 2013 EB
_g1
_ieBOOK
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_z06-04-17
988 _aEBOOK, EBSPRINGERrevisado
998 _am
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_b04-05-17
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