000			02683nam a22003495i 4500
001			75994
003			ES-MaUEC
005			20230202101836.0
007			cr nn 008mamaa
008			130930s2013 xxu| s |||| 0|eng d
020			_a9781461476900
040			_aES-MaUEC
050		4	_aQR185.7 _bS458 2013 EB
100	1		_aSelvarajoo, Kumar _984782 _0Local
245	1	0	_aImmuno Systems Biology : _bA macroscopic approach for immune cell signaling _cby Kumar Selvarajoo
260			_aNew York _bSpringer International Publishing _c2013
300			_a1 recurso en línea (IX, 146 p.) 69 il., 61 il. col.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aSystems Biology _x2191-222X _v3
520			_aTechnological advances of modern biology have generated high volumes of â€õmicsâ€{u0921}ta. The natural precedence has been to put the complex information together, so that it will lead to spectacular scientific discoveries and medical breakthroughs. In this light, tremendous efforts worldwide are reshaping biological research by integrating with information science. Despite the â€s̃ystems biologyâ€{u0966}forts, for major illnesses, such as proinflammatory diseases and cancer, there is clear clinical evidence that even the most current therapies, at best, control transient response and subdue to the robust adaptability of the disease state. Hence, there is a need for system-levels understanding of bio-complexity. Kumar Selvarajoo brings attention to fundamental questions governing sophisticated behaviors of the mammalian immune system. To tackle some of the complex issues, the book introduces perturbation-response approach, using the law of physics (mass flow conservation), as a means to interpret the dynamic response of major proinflammatory pathways of the immune and cancer cells. Overall, the book provides an illustrated journey that explains biological cell signaling in simple terms.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisado
650		7	_aInmunología _0comprobar BNE19900958507 _2embne _9138330
830		0	_aSystems Biology _x2191-222X _v3 _9133186 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-7690-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781461476900
907			_a.b12816127 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b26-02-17 _cm _dz _eo _feng _gxxu _h0
945			_aQR185.7 S458 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11545501 _z06-04-17
999			_c75994 _d75994 _x1