000			02639nam a22003375i 4500
001			75981
003			ES-MaUEC
005			20230207040204.0
007			cr nn 008mamaa
008			130709s2013 xxu| s |||| 0|eng d
020			_a9781461472940
040			_aES-MaUEC
050		4	_aQR201.A37 _bW535 2013 EB
100	1		_aWick, W David _984759 _0Local
245	1	0	_aWar in the Body : _bThe Evolutionary Arms Race Between HIV and the Human Immune System and the Implications for Vaccines _cby W David Wick, Otto O Yang
260			_aNew York _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XIX, 298 p.) 51 il., 4 il. col.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
520			_aIn the relatively few decades since the introduction of HIV into the human population, variants of the virus have diverged to such an extent that, were the discussion about something other than viruses, said variants could easily be classified as differentÂ{u3C25}cies. This book will consider these evolutionary variations, as well as the different and, at times, opposing theories attempting to explain them. It will compare and contrast the ways in which the immune system and drugs affect the virus's evolution, and the implications of these for vaccine development. The issue will be explored and explained through "ecological genetics," which postulatesÂ{u4A21}tÂ{u1B2C} living organisms have, besides rivals, enemies. This is divergent from the more traditional school of "population genetics," which emphasizes that evolution occurs among rival species (or variants thereof) that competeÂ{u6BF2} niches or resources in a fixed, unreactive environment. Both models will be formulatedÂ{u5CE9}ng mathematical models, which will be included in the book. Finally, it will consider the possibilities for designing a vaccine that blocks HIV from escaping the immune system.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisado
650		7	_aInfecciones por VIH _0comprobar BNE19982759317 _2embne _9154434
700	1		_aYang, Otto O _984760 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-7294-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781461472940
907			_a.b12815998 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b26-02-17 _cm _dz _eo _feng _gxxu _h0
945			_aQR201.A37 W535 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11545379 _z06-04-17
999			_c75981 _d75981 _x1