000 02478nam a22003255i 4500
001 75942
003 ES-MaUEC
005 20230202101818.0
007 cr nn 008mamaa
008 130217s2013 xxu| s |||| 0|eng d
020 _a9781461461821
040 _aES-MaUEC
050 4 _aRC280.P7
_bA53 2013 EB
245 0 0 _aAndrogen-Responsive genes in prostate cancer :
_bregulation, function and clinical applications
_cedited by Zhou Wang
260 _aNew York
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (IX, 348 p.)
_b43 il., 35 il. col.
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
520 _aRecent studies demonstrated a key role of the androgen receptor in the development of castration-recurrent or -resistant prostate cancer (CRPC), which is deadly and in urgent need of more effective therapies. Understanding the functions of androgen-responsive genes and their regulation and deregulation in prostate cancer progression may lead to new approaches to prevent and treat prostate cancer patients. This book provides an up-to-date review of the overall androgen-responsive gene expression program and the regulation, function, and clinical relevance of both protein coding and non-coding androgen-responsive genes. Experts in the field of androgen action and prostate cancer research discussed the importance of DNA elements, chromatin structure, cellular signaling, and cell-cell interactions in the regulation of androgen-responsive genes in the context of prostate cancer progression, including the development of CRPC. This book is intended for individuals interested in cancer endocrinology and medical and healthcare professionals involved in prostate cancer research
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGERrevisado
650 7 _aPróstata
_xCáncer
_0comprobar BNE19901355947
_2embne
_9182337
700 1 _aWang, Zhou
_eeditor literario
_984678
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-6182-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9781461461821
907 _a.b12815603
_b10-10-17
_c01-10-14
998 _am
_a_alco
_a_vill
_b23-03-17
_cm
_dz
_eb
_feng
_gxxu
_h0
945 _aRC280.P7 A53 2013 EB
_g1
_ieBOOK
_j0
_lmae
_o-
_pEUR0.00
_q-
_r-
_sb
_t15
_u0
_v0
_w0
_x0
_y.i11544983
_z06-04-17
999 _c75942
_d75942
_x1