000 05047nam a22004095i 4500
001 75917
003 ES-MaUEC
005 20230207040202.0
007 cr nn 008mamaa
008 130125s2013 xxu| s |||| 0|eng d
020 _a9781461457114
024 7 _a10.1007/978-1-4614-5711-4
_2doi
040 _aES-MaUEC
050 4 _aQH588.S83
_bM47 2013 EB
082 0 4 _a571.6
245 0 0 _aMesenchymal stromal cells :
_bbiology and clinical applications
_cedited by Peiman Hematti, Armand Keating
260 _aNew York
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (XXVI, 695 p.)
_b61 ilustraciones, 40 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aStem Cell Biology and Regenerative Medicine
505 0 _aMSCs in regenerative medicine: A perspective -- MSCs: Changing hypotheses, paradigms, and controversies on mechanisms of action in repairing tissues -- MSCs:℗¡ the need to rethink -- Characterization of MSCs: From early studies to the present -- MSCs as therapeutics -- MSC niche for hematopoiesis -- Immunomodulatory properties of MSCs -- MSCs and the innate immune system: A balancing act -- MSCs: paracrine effects -- Cross-talk between MSCs and their environments -- Human MSCs from bone marrow, umbilical cord blood and adipose tissue: all the same? -- MSCs in solid tumors and hematological malignancies: from basic biology to therapeutic potential -- MSC studies in large animal Models -- Defining the potential of MSCs with a prenatal large animal Model -- Bench-to-bedside development of MSC based therapies: A multidisciplinary approach -- GMP production of MSCs -- MSCs: The USA regulatory perspective -- MSCs: Clinical applications and European regulatory aspects -- Stem cell treatments around the world: boon or bane? -- Safety issues in MSC therapy -- In Vivo imaging of MSCs -- National Heart, Lung, and Blood Institute support of cellular therapies regenerative medicine -- MSC therapy of inborn errors -- MSCs for enhancement of hematopoietic progenitor cell engraftment and poor graft function -- MSCs for graft-versus-host disease -- MSCs in paediatric hematopoietic stem cell transplantation -- MSCs for ex vivo expansion of umbilical cord blood cells -- MSCs for autoimmune disorders -- MSCs for induction of solid organ allograft acceptance -- MSCs for gastrointestinal disorders -- MSCs for cardiac repair -- MSCs for acute lung injury -- MSCs for diabetes -- MSCs for renal repair -- MSCs for the treatment of stroke, spinal cord injury, and traumatic brain injury: From bench work to clinical trials -- MSCs in reconstructive surgery -- MSCs in orthopedic surgery -- Adipose tissue derived MSCs: Moving to the clinic
520 _aMesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress has become exponential over the past decade due mainly to the broad therapeutic potential of these cells. ℗¡℗¡However, MSC studies have also been subject to controversy and increasing scrutiny as new mechanisms of action are reported and ever-expanding therapeutic applications pursued. In this book, leading authorities from all over the world, who are actively involved in this field, provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with MSCs. ℗¡This cutting edge book is the ideal resource for scientists and clinicians interested in pursuing an important and rapidly developing field of research that will eventually help patients and address urgent unmet medical needs. Features include: Coverage of the biology of MSCs, latest understanding of℗¡ mechanisms of action, and role in tissue homeostasis and regeneration Identifying the potential of MSCs in proceeding from bench to bedside from regulatory , GMP production, ethical and safety aspects Critical analysis of clinical studies and the potential of MSCs to treat a wide variety of human diseases and tissues
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGERrevisado
650 7 _aCélulas madre
_0comprobar BNE20022110396
_2embne
_9160528
650 7 _aBiotecnología
_0comprobar BNE19900991605
_2embne
_9140931
700 1 _aHematti, Peiman
_eeditor literario
_984638
_0Local
700 1 _aKeating, Armand
_eeditor literario
_984639
_0Local
830 0 _aStem Cell Biology and Regenerative Medicine
_9133169
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-5711-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9781461457114
907 _a.b12815354
_b10-10-17
_c01-10-14
998 _am
_a_alco
_a_vill
_b04-05-17
_cm
_dz
_eb
_feng
_gxxu
_h0
945 _aQH588 .S83 M43 2013 EB
_g1
_ieBOOK
_j0
_lmae
_o-
_pEUR0.00
_q-
_r-
_sb
_t15
_u0
_v0
_w0
_x0
_y.i11544739
_z06-04-17
999 _c75917
_d75917
_x1